58814-58-7Relevant academic research and scientific papers
Modification of 3-arylisoquinolines into 3,4-diarylisoquinolines and assessment of their cytotoxicity and topoisomerase inhibition
Khadka, Daulat Bikram,Woo, Hyunjung,Yang, Su Hui,Zhao, Chao,Jin, Yifeng,Le, Thanh Nguyen,Kwon, Youngjoo,Cho, Won-Jea
, p. 583 - 607 (2015)
Inspired by the initial success of the monoarylisoquinolines and the quest to identify more potent and selective anticancer agents with topoisomerase (topo) inhibitory activity, series of diarylisoquinolines (3,4-diarylisoquinolones and 3,4-diarylisoquino
Antiviral activity of isoquinolone derivatives against influenza viruses and their cytotoxicity
Jang, Yejin,Han, Jinhe,Li, Xiaoli,Shin, Hyunjin,Cho, Won-Jea,Kim, Meehyein
, (2021/07/19)
Influenza viruses are one of the major causative agents for human respiratory infections. Currently, vaccines and antivirals approved for preventing and treating viral infections are available. However, limited protection efficacy and frequent emergence o
Fused pyridine derivatives
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Example 8, (2010/01/30)
The present provides a condensed pyridine compound (I) represented by the following formula: (wherein, R2represents ring A represents benzene ring, pyridine ring, thiophene ring or furan ring; and B represents its pharmaceutically acceptable salt or hydrates thereof, which is a clinically useful medicament having a serotonin antagonism, in particular, that for treating, ameliorating or preventing spastic paralysis or central muscle relaxants for ameliorating myotonia.
