58821-97-9

Usage

InChI:InChI=1/C15H20O3/c1-15(2)9-8-12-10-11(4-3-5-14(16)17)6-7-13(12)18-15/h6-7,10H,3-5,8-9H2,1-2H3,(H,16,17)

Upstream product

• 7021-11-6 4-(4-hydroxyphenyl)butanoic acid 
• 870-63-3 prenyl bromide 
• 4521-28-2 4-(4-Methoxyphenyl)butyric acid 
• 109996-87-4 4-(2,2-Dimethyl-chroman-6-yl)-4-oxo-butyric acid methyl ester 

Relevant academic research and scientific papers

Design, synthesis, and testing of potential antisickling agents. 10. (2,2-Dimethylchroman-6-yl)alkanoic acids

Five (2,2-dimethylchroman-6-yl)alkanoic acids were synthesized and tested for antigelling activities. It was envisioned that these agents might bind via hydrophobic bonding to nonpolar sites of the 'donor-acceptor' regions of hemoglobin S. Several (2,2-di

A Convenient Solvent-specific Synthesis of 4-butyric acid

Three types of reaction, esterification, C-alkenylation, and O-alkenylation, have been observed between the di-anion (4) and 1-bromo-3-methylbut-2-ene (5) in different solvent systems.Our studies of the effect of the medium on the behavior of the di-anion (4) towards electrophilic attack by the bromo-alkene (5) resulted in the synthesis of analogues (2) and (6d) of a known anti-sickling agent (3) in high yiel.The regioselectivity of the alkylation reactions is rationalised in terms of solvent polarity.