58848-61-6Relevant academic research and scientific papers
New chiral cyclooctatriene-based polycyclic architectures
Pieters, Gregory,Gaucher, Anne,Marrot, Jerome,Maurel, Francois,Naubron, Jean-Valere,Jean, Marion,Vanthuyne, Nicolas,Crassous, Jeanne,Prim, Damien
, p. 4450 - 4453 (2011)
The synthesis and properties of new chiral polycyclic architectures that display both helicity and a saddle-type shape are described. The enantiomers have been separated, and their absolute configuration was determined by VCD and ECD. The unprecedented mo
Synthesis and molecular structure of symmetrical 1,8-diarylnaphthalenes
Pieters, Gregory,Terrasson, Vincent,Gaucher, Anne,Prim, Damien,Marrot, Jerome
experimental part, p. 5800 - 5806 (2011/01/12)
The synthesis of substituted 1,8-diarylnaphthalenes is reported. A bis-Suzuki coupling strategy starting from 1,8-dibromonaphthalene provides a useful and general route to the 1,8-diarylnaphthalene scaffold. In this context, N-heterocyclic benzhydrylamine ligands, in combination with PdCl2, were found to form especially efficient catalytic systems. The syn/anti ratios were determined in solution from their 1H NMR spectra. Analysis of the molecular structure in the solid state for six new targets focused on deformation of the naphthalene core. The observed lack of planarity occurs as a result of several parameters, such as the nature and number of substituents, the substitution pattern as well as steric congestion and π-stacking between cofacial rings. The synthesis of substituted 1,8-diarylnaphthalenes using bis-Suzuki coupling of 1,8-dibromonaphathalene is described. Molecular structures in the solid state for six new compounds were analyzed. The influence of several parameters on naphthalene core deformation are described.
First expeditious synthesis of 6,11-diamino-[6]carbohelicenes
Pieters, Gregory,Gaucher, Anne,Prim, Damien,Marrot, Jerome
supporting information; experimental part, p. 4827 - 4828 (2009/12/08)
The first synthesis of 6,11-diamino-[6]carbohelicenes is described: the short 5 step sequence involves Suzuki-Miyaura coupling, functional group transformations and electrophilic aromatic cyclisation; the original strategy allows the preparation of di- an
