58848-83-2Relevant academic research and scientific papers
With antibiotic compound of ability and its preparation method and use thereof
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Paragraph 0022; 0023; 0024, (2017/08/25)
The invention discloses application of a 3-aryl-6-aryl-7H-thiazolo [3,2-b]-1,2,4-triazine-7-ketone derivative with a general formula I shown in the description to an antibacterial drug. In the general formula I, R1 and R2 are methyl, halogen, hydroxyl, methoxyl, acetyl, propionyl, formylphenyl, carbamoyl-methoxy-benzyl, 4-methylanilino formyl-methoxyl or chloroaniline formyl-methoxyl respectively and independently. The 3-aryl-6-aryl-7H-thiazolo [3,2-b]-1,2,4-triazine-7-ketone derivative, namely an antibacterial compound provided by the invention, has obvious inhibiting effects on methicillin-resistant staphylococcus aureus, escherichia coli, pseudomonas aeruginosa and a variety of bacteria, and can be used for the preparation of the antibacterial drug.
