58862-92-3Relevant academic research and scientific papers
INHIBITORY EFFECT OF HYDROXIDE IONS ON THE DEGRADATION OF β-DICARBONYL COMPOUNDS PRODUCED BY THE RING OPENING OF CHROMONES IN ALKALINE MEDIUM
Zsuga, M.,Szabo, V.,Korodi, F.
, p. 111 - 119 (2007/10/02)
A kinetic investigation is reported of the degradation of β-dicarbonyl phenolates (1) and enolates (2) produced by ring cleavage reaction of chromone, flavone, isoflavone and the corresponding 2-hydroxychromanones.Hydroxide ions were found to inhibit the cleavage of these compounds, which effect had been unknown in the field of chromonoids and β-dicarbonyl compouns.The inhibitory effect can be expressed by the equation k=(kd1K*+kd22)/(K*+).The reaction rate constants (kd1 and kd2), the equilibrium constants (K* and K), as well as the activation energy and entrophy of the degradation reaction were determined.Based upon the change of the activation energy and entropy, hydratation of the phenolates (1) and enolates (2) was found to play a very important part in the degradation.
