58863-48-2

Upstream product

• 271-89-6 1-benzofurane 
• 4265-25-2 2-methylbenzofuran 

Downstream Products

• 66022-00-2 1-hydroxy-2-(prop-1-ynyl)benzene 
• 3265-74-5 2-methyl-1-benzofuran-3-carboxylic acid 
• 93782-20-8 -1-propyne 
• 4265-25-2 2-methylbenzofuran 
• 1585983-48-7 1-(2-methyl-3-benzofuranyl)-2-(2-methylphenyl)perfluorocyclopentene 
• 1364381-25-8 1-(2-methyl-3-benzofuryl)-2-(2-methyl-5-phenyl-3-thienyl)perfluorocyclopentene 
• 37797-72-1 2-(2-methylbenzofuran-3-yl)acetonitrile 
• 1416881-64-5 (E)-N-(2-(2-methylbenzofuran-3-yl)ethyl)-3-(3,4,5-trimethoxyphenyl)acrylamide 
• 1427283-27-9 1-(2-methyl-1-benzofuran-3-yl)-2-[2-methyl-5-(4-1,3-dioxolane-phenyl)-3-thienyl]perfluorocyclopentene 
• 1586038-80-3 1-(2-methyl-1-benzofuran-3-yl)-2-[2-methyl-5-(4-benzaldehyde)-3-thienyl]perfluorocyclopentene 
• 1364381-31-6 C₂₄H₁₅F₆NOS 
• 1345121-99-4 2,6-difluoro-N-(5-(2-methylbenzofuran-3-yl)pyrazin-2-yl)benzamide 

Relevant academic research and scientific papers

Photochromic reaction behavior and thermal stability of thiophene-S,S-dioxidized diarylethenes having a benzofuryl group

Diarylethenes having a benzofuryl group and their thiophene-S,S-dioxidized diarylethenes were synthesized and their optical properties and thermal stability were investigated. Upon oxidation of the thiophene ring, the optical properties such as absorption

A light triggered optical and chiroptical switch based on a homochiral Eu2L3helicate

Optical and chiroptical photoswitches have found potential applications in advanced information technologies. Herein, a pair of chiral triple-stranded helicates [Eu2(o-LRR)3](TOf)6and [Eu2(o-LSS)3](TOf)6, which have chirality, luminescence and light stimuli-responsive properties, have been designed and synthesized. The ligands o-LRR/SSare composed of photochromic diarylethene moieties as spacers and two chiral 2,6-dipicolinic amides as coordination units. Through the comprehensive spectral characteristics in combination with semiempirical geometry optimization using the Sparkle/RM1 model, it was confirmed that (R/S)-1-phenylethanamines decorated at the terminals of ligands successfully controlled the stereoselective self-assembly of the helicates. Upon alternating UV and visible light irradiation, the diarylethene experienced a reversible change between a colorless open-ring state and a pink closed-ring state. This photochromic process caused variations in the electronic structure and ligand conformation, and led to the presence of light-responsive optical (UV and PL) and chiroptical (ECD and CPL) switching properties. The helicate may, therefore, be considered as a completely reversible +/- ECD and on/off CPL switch. Furthermore, on the basis of these light-switchable optical properties, the INHIBIT and IMPLICATION logic gates were fabricated.

FUSED PYRIMIDINE COMPOUND, INTERMEDIATE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND APPLICATION THEREOF

Disclosed are a fused pyrimidine compound, an intermediate, a preparation method therefor, and a composition and an application thereof. The present invention provides a fused pyrimidine compound shown in formula I, pharmaceutically acceptable salt, hydrate, solvate, and an optical isomer or prodrug of the compound. The present invention further provides applications of the fused pyrimidine compound shown in formula I, the pharmaceutically acceptable salt, the hydrate, solvate, and the optical isomer or the prodrug of the compound in the preparing drugs for curing and/or preventing a kinase-related disease. The fused pyrimidine compound I of the present invention is an efficient PI3 kinase depressor, and can be used to prepare drugs for preventing and/or curing cell-proliferation diseases such as cancer, infection, inflammation, and an autoimmune disease.

The effects of heteroaryl ring on the photochromism of diarylethenes with a naphthalene moiety

Three new asymmetrical naphthalene-containing diarylethenes with different heteroaryl groups have been synthesized to investigate the heteroaryl effects on their properties. The three diarylethenes exhibited distinctive photochromism with good thermal stability, which may be attributed to the different heteroaryl effects. Their cycloreversion quantum yields increased in the order of 2-methylbenzofuran 2-methylbenzothiophene 1,2-dimethylindole, while the cyclization quantum yields exhibited a reverse trend. Compared to indole and benzothiophene, the benzofuran moiety could effectively shift the absorption maximum to a shorter wavelength and notably enhance the cyclization quantum yield and fluorescence quantum yield of the diarylethene. The results indicated that the category of heteroaryl groups played a vital role during the process of photoisomerization of naphthalene-containing diarylethene derivatives.

Regioselective copper-catalyzed chlorination and bromination of arenes with O2 as the oxidant

Electron-rich aromatic C-H bonds undergo regioselective chlorination and bromination in the presence of CuX2, LiX (X = Cl, Br) and molecular oxygen. Preliminary mechanistic insights suggest that the bromination and chlorination reactions proceed by different pathways.

Photochromism of bis(2-alkyl-1-benzofuran-3-yl)perfluorocyclopentene derivatives

Photochromic diarylethene derivatives having benzofuran heteroaryl groups, bis(2-methyl-1-benzofuran-3-yl)perfluorocyclopentene and bis(2-butyl-1- benzofuran-3-yl)perfluorocyclopentene, were synthesized, and their photochromic performance was examined in hexane solution as well as in the single-crystalline phase. The compounds exhibited photochromic reactivity even in the single-crystalline phase.