58863-48-2Relevant articles and documents
Photochromic reaction behavior and thermal stability of thiophene-S,S-dioxidized diarylethenes having a benzofuryl group
Tanaka, Koki,Kitagawa, Daichi,Kobatake, Seiya
, p. 2364 - 2368 (2016)
Diarylethenes having a benzofuryl group and their thiophene-S,S-dioxidized diarylethenes were synthesized and their optical properties and thermal stability were investigated. Upon oxidation of the thiophene ring, the optical properties such as absorption
FUSED PYRIMIDINE COMPOUND, INTERMEDIATE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND APPLICATION THEREOF
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Paragraph 0151; 0152, (2016/08/17)
Disclosed are a fused pyrimidine compound, an intermediate, a preparation method therefor, and a composition and an application thereof. The present invention provides a fused pyrimidine compound shown in formula I, pharmaceutically acceptable salt, hydrate, solvate, and an optical isomer or prodrug of the compound. The present invention further provides applications of the fused pyrimidine compound shown in formula I, the pharmaceutically acceptable salt, the hydrate, solvate, and the optical isomer or the prodrug of the compound in the preparing drugs for curing and/or preventing a kinase-related disease. The fused pyrimidine compound I of the present invention is an efficient PI3 kinase depressor, and can be used to prepare drugs for preventing and/or curing cell-proliferation diseases such as cancer, infection, inflammation, and an autoimmune disease.
Regioselective copper-catalyzed chlorination and bromination of arenes with O2 as the oxidant
Yang, Lujuan,Lu, Zhan,Stahl, Shannon S.
supporting information; experimental part, p. 6460 - 6462 (2010/03/04)
Electron-rich aromatic C-H bonds undergo regioselective chlorination and bromination in the presence of CuX2, LiX (X = Cl, Br) and molecular oxygen. Preliminary mechanistic insights suggest that the bromination and chlorination reactions proceed by different pathways.