5887-58-1Relevant academic research and scientific papers
2-Aryl-substituted benzo-anellated 5-membered heterocycles as potential effectors in the cardiovascular system. Part 2
Rose
, p. 775 - 777 (2007/10/02)
In the course of investigations on structure-activity relationships of fostedil-and sulmazole-analoguesly fused 5-membered heterocycles, 1,3-benzimidazoles were obtained by simple cyclisation. In vitro experiments on isolated organs demonstrate markedly positive inotropic effects of some derivatives, whereas others exert both relaxing activity on smooth musculature in vitro and antihypertensive effects in vivo. Moreover they exhibit fungicide properties in vitro.
