588708-16-1

Basic information

• Product Name: N-(4-methoxybenzyl)-1,3-diphenyl-2-propanimine
• Synonyms: N-(4-methoxybenzyl)-1,3-diphenyl-2-propanimine
• CAS NO: 588708-16-1
• Molecular Weight: 329.442
• Mol File: 588708-16-1.mol

Chemical Properties

• CAS DataBase Reference: N-(4-methoxybenzyl)-1,3-diphenyl-2-propanimine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methoxybenzyl)-1,3-diphenyl-2-propanimine(588708-16-1)
• EPA Substance Registry System: N-(4-methoxybenzyl)-1,3-diphenyl-2-propanimine(588708-16-1)

Safety Data

• Hazardous Substances Data: 588708-16-1(Hazardous Substances Data)

Upstream product

• 2393-23-9 4-methoxy-benzylamine 
• 102-04-5 1,3-Diphenylpropanone 

Downstream Products

• 6278-96-2 2-amino-2-benzyl-3-phenylpropanoic acid 
• 94164-89-3 N-acetyl-α,α-dibenzylglycine 
• 658044-12-3 N-benzoyl-α,α-dibenzylglycine cyclohexylamide 
• 135906-34-2 4,4-dibenzyl-2-phenyl-1,3-oxazol-5(4H)-one 
• 54132-09-1 N-benzoyl-α,α-dibenzylglycine 
• 658044-04-3 N-benzoyl-N-(4-methoxybenzyl)-α,α-dibenzylglycine 4-methoxybenzyl amide 
• 658044-06-5 N-benzoyl-N-(4-methoxybenzyl)-α,α-dibenzylglycine cyclohexyl amide 
• 658044-03-2 N-phenylacetyl-N-(4-methoxybenzyl)-α,α-dibenzylglycine 4-methoxybenzyl amide 
• 658044-05-4 N-phenylacetyl-N-(4-methoxybenzyl)-α,α-dibenzylglycine cyclohexyl amide 
• 588708-31-0 N-acetyl-N-(4-methoxybenzyl)-α,α-dibenzylglycine 2,4-dimethoxybenzyl amide 
• 588708-30-9 N-acetyl-N-(4-methoxybenzyl)-α,α-dibenzylglycine 4-methoxybenzyl amide 
• 588708-29-6 N-acetyl-N-(4-methoxybenzyl)-α,α-dibenzylglycine 2,4-dimethoxyphenyl amide 
• 588708-28-5 N-acetyl-N-(4-methoxybenzyl)-α,α-dibenzylglycine 4-methoxyphenyl amide 
• 588708-27-4 N-acetyl-N-(4-methoxybenzyl)-α,α-dibenzylglycylglycine ethyl ester 

Relevant articles and documents

An improved approach for the synthesis of α,α-dialkyl glycine derivatives by the Ugi-Passerini reaction

A general and simple strategy for routine peptide synthesis with α,α-dialkyl glycines taking advantage of the four-component Ugi-Passerini reaction is presented. The isonitrile required for the reaction can be relatively simple and its selection based on cost, as the group it generates is easily removed under acidic conditions; in addition, this removal is not visibly affected by the bulkiness of the α-alkyl groups. Being a good leaving group from the N-terminal amino group of the amino acid, 4-methoxybenzyl was the choice for the amine component of the reaction. The method is illustrated with the synthesis of a series of acyl derivatives of several α,α-dialkyl glycines. The preparation of the latter compounds is also reported.