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3-(3-AMino-1H-pyrazol-1-yl)propanenitrile is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

58876-75-8

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58876-75-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 58876-75-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,8,7 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 58876-75:
(7*5)+(6*8)+(5*8)+(4*7)+(3*6)+(2*7)+(1*5)=188
188 % 10 = 8
So 58876-75-8 is a valid CAS Registry Number.

58876-75-8Upstream product

58876-75-8Downstream Products

58876-75-8Relevant academic research and scientific papers

(PYRIDIN-2-YL)AMINE DERIVATIVES AS TGF-BETA R1 (ALK5) INHIBITORS FOR THE TREATMENT OF CANCER

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Paragraph 00369, (2020/07/15)

The present invention relates to pharmaceutical compounds, compositions and methods, especially as they are related to compositions and methods for the treatment and/or prevention of a proliferation disorder associated with ΤGFβR1 activity, such as a cancer or fibrosis. The invention provides compounds of Formula (I) and Formula (II) as further described herein having an acidic moiety that enhances tissue specificity for targeted tissues and organs. The invention includes pharmaceutical compositions, pharmaceutical combinations, and methods of use of these compounds for treating conditions including cancer or fibrosis.

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