589-57-1Relevant articles and documents
REACTION OF ESTERS OF N-BUTYL-N-ISOBUTENYLAMIDO- AND BIS(N-BUTYL-N-ISOBUTENYLAMIDO)PHOSPHORUS ACIDS WITH OXYGEN AND HALOGEN-CONTAINING COMPOUNDS
Kibardin, A.M.,Gryaznov, P.I.,Gazizov, T.Kh.,Pudovik, A.N.
, p. 2166 - 2168 (1984)
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CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES
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Page/Page column 71; 72, (2018/03/25)
Disclosed are novel conjugates and processes for the preparation thereof. A process for the preparation of alkene- or alkyne-phosphonamidates comprises the steps of (I) reacting a compound of formula (III), with an azide of formula (IV), to prepare a compound of formula (V), reacting a compound of formula (V) with a thiol-containing molecule of formula (VI), resulting in a compound of formula (VII).
Synthetic method of methyl phosphite and glufosinate-ammonium
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Paragraph 0031; 0049, (2016/11/07)
The invention discloses a synthetic method of methyl phosphite and glufosinate-ammonium. The method comprises the steps: with phosphorus pentasulfide as a starting material, then carrying out vulcanization reaction, chlorination reaction, water washing and distillation purification, then carrying out catalytic hydrogenation to obtain chloride phosphite (III), and next carrying out Grignard reaction to obtain methyl phosphite (IV), wherein R is C1-C4 alkyl. The method comprises the steps: with phosphorus pentasulfide as the starting material, then carrying out vulcanization reaction, chlorination reaction, water washing and distillation purification, then carrying out catalytic hydrogenation to obtain chloride phosphite, next carrying out Grignard reaction to synthesize methyl phosphite (IV), and thus obtaining the final product glufosinate-ammonium through a Strecker route of the prior art. The synthetic yield is increased, methyl phosphorus dichloride and other unstable corrosive intermediates cannot be produced, the discharge of three-waste substances is reduced, and environment-friendly costs and pressure are reduced.
