58950-88-2

Basic information

• Product Name: (4-Methylsulfanyl-phenyl)-oxo-acetaldehyde
• Synonyms: (4-Methylsulfanyl-phenyl)-oxo-acetaldehyde
• CAS NO: 58950-88-2
• Molecular Weight: 180.227
• Mol File: 58950-88-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-Methylsulfanyl-phenyl)-oxo-acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Methylsulfanyl-phenyl)-oxo-acetaldehyde(58950-88-2)
• EPA Substance Registry System: (4-Methylsulfanyl-phenyl)-oxo-acetaldehyde(58950-88-2)

Safety Data

• Hazardous Substances Data: 58950-88-2(Hazardous Substances Data)

Upstream product

• 1778-09-2 4-(Methylthio)acetophenone 

Relevant articles and documents

One-pot three-component reactions of methyl ketones, phenols and a nucleophile: An expedient way to synthesize densely substituted benzofurans

Three-component reactions of phenylglyoxal monohydrate, phenols, and indoles were developed with the aid of acid-catalyst, which produced various densely substituted benzofurans with good to excellent yields. On the basis of this observation, a one-pot, step-wise reaction was developed by using methyl ketones instead of using phenylglyoxal component in I2/DMSO system. At last, three-component reaction offered a useful way to synthesize densely substituted benzofurans starting from simple and easily available substrates. The indole component can be replaced by some other nucleophiles, such as 1,2,4-trimethoxybenzene and thiophenol.