58952-00-4

Upstream product

• 39506-61-1 2-hydroxy-5-methylbenzamide 
• 34265-58-2 ethyl 5-methylsalicylate 

Downstream Products

• 79173-74-3 2-(5-methyl-2-hydroxyphenyl)-thiazoline-4-carboxylic acid sodium 
• 1271307-84-6 C₁₆H₁₃NOS 

Relevant academic research and scientific papers

Thiazole-based chemosensor II: Synthesis and fluorescence sensing of fluoride ions based on inhibition of ESIPT

Novel chemosensors based on 2-(2′-hydroxyphenyl)-4-phenylthiazole were synthesized and their anion sensing behaviors were investigated. Sensors 1 and 2 show fluoride ion selective behaviors related to their absorption and emission spectra amongst F-, CH3CO2-, H2PO4-, Cl-, Br-, I-, ClO4-, NO3-, and HSO4- anions. Sensor 2 shows color change upon interaction with F-. Interactions of 1, 2 and 3 with F- cause a red-shift in UV-vis absorption and a large Stokes shift in fluorescence emission due to the inhibition of ESIPT induced by the deprotonation of phenolic proton by F-. Springer Science+Business Media B.V. 2009.

Process for the preparation of aromatic thiocarboxylic acid amides

Aromatic thiocarboxylic acid amides are prepared by reaction of aromatic hydrocarbons with hydrogen thiocyanate or a salt of thiocyanic acid in at least 90% hydrofluoric acid. The reaction can be carried out in one single operation without the use of a Lewis acid or another catalyst. The thiocarboxylic acid amides obtained are known from the literature and serve as preliminary products for the preparation of nitriles, amides, carboxylic acids, heterocyclic compounds and the manufacture of plant protecting agents and pharmaceuticals.