59-61-0

Basic information

• Product Name: Dichloroisoproterenol
• Synonyms: Dichloroisoproterenol;3,4-Dichloro-α-(isopropylaminomethyl)benzyl alcohol;3,4-Dichloro-α-[(isopropylamino)methyl]benzyl alcohol;3,4-Dichloro-α-[[(1-methylethyl)amino]methyl]benzenemethanol;Dichlorisoproterenol;1-(3,4-Dichlorophenyl)-2-isopropylaminoethanol;Aids059770;Aids-059770
• CAS NO: 59-61-0
• Molecular Formula: C₁₁H₁₅Cl₂NO
• Molecular Weight: 280.1477
• Mol File: 59-61-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 122.4°C (rough estimate)
• Flash Point: 172.1°C
• Appearance: /
• Density: 1.2061 (rough estimate)
• Vapor Pressure: 7.67E-06mmHg at 25°C
• Refractive Index: 1.5490 (estimate)
• PKA: 13.32±0.20(Predicted)
• CAS DataBase Reference: Dichloroisoproterenol(CAS DataBase Reference)
• NIST Chemistry Reference: Dichloroisoproterenol(59-61-0)
• EPA Substance Registry System: Dichloroisoproterenol(59-61-0)

Safety Data

• Hazardous Substances Data: 59-61-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H15Cl2NO/c1-7(2)14-6-11(15)8-3-4-9(12)10(13)5-8/h3-5,7,11,14-15H,6H2,1-2H3/t11-/m0/s1

Upstream product

• 75-31-0 isopropylamine 
• 38923-36-3 2-(3,4-dichlorophenyl)-2-oxoacetaldehyde 
• 6287-38-3 3,4-dichlorobenzaldehyde 

Downstream Products

• 99840-24-1 [2-Chloro-2-(3,4-dichloro-phenyl)-ethyl]-isopropyl-amine 
• 20879-18-9 (+)-Dichloroisoproterenol 
• 84775-12-2 C₁₂H₃₀N₆*C₁₁H₁₅Cl₂NO*3H⁽¹⁺⁾ 

Relevant articles and documents

Method for preparing beta-arylamino alcohol drugs such as tulobuterol, clorprenaline, dichloroisoprenaline and sotalol

The invention provides a method for preparing beta-arylamino alcohol drugs such as tulobuterol, clorprenaline, dichloroisoprenaline and sotalol. The beta-arylamino alcohol drugs have a chemical structure represented by a formula 4 shown in the description. The method comprises the following steps: (1) reacting arylethanone represented by a formula 1 shown in the description with a halogenating agent and sulfoxide to obtain arylglyoxal represented by a formula 2 shown in the description and or 1,1-dihydroxyarylethanone represented by a formula 3 shown in the description; and (2) performing a nucleophilic addition reaction on the arylglyoxal represented by the formula 2 and/or the 1,1-dihydroxyarylethanone represented by the formula 3 and an amine compound having a chemical formula of R1-NH2, and performing a reductive amination reaction in the presence of a reducing agent to obtain the beta-arylamino alcohol drugs.