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Neostigmine is a quaternary ammonium ion with an anilinium ion core, featuring three methyl substituents on the aniline nitrogen and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It functions as a parasympathomimetic agent and acts as a reversible acetylcholinesterase inhibitor.

59-99-4

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59-99-4 Usage

Uses

Used in Pharmaceutical Industry:
Neostigmine is used as a medication for the treatment of myasthenia gravis, a neuromuscular disorder that causes muscle weakness. It works by inhibiting the enzyme acetylcholinesterase, which in turn increases the concentration of acetylcholine at the neuromuscular junction, enhancing muscle contractions and improving muscle strength.
Additionally, Neostigmine is used as a parasympathomimetic agent in the treatment of postoperative urinary retention, a condition where the bladder is unable to empty itself after surgery. By inhibiting acetylcholinesterase, it increases the levels of acetylcholine, leading to enhanced parasympathetic activity and improved bladder function.
Used in Veterinary Medicine:
In veterinary medicine, Neostigmine is used as a treatment for megacolon, a condition characterized by an enlarged colon and difficulty in passing feces. It helps to stimulate bowel movement by increasing the levels of acetylcholine, which promotes muscle contractions in the gastrointestinal tract.
Used in Research Applications:
Neostigmine is also utilized in research settings as a tool to study the effects of acetylcholinesterase inhibition on various physiological processes. It is particularly useful in investigating the role of acetylcholine in the central and peripheral nervous systems, as well as its involvement in cognitive functions and neurodegenerative diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 59-99-4 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 5 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 59-99:
(4*5)+(3*9)+(2*9)+(1*9)=74
74 % 10 = 4
So 59-99-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H19N2O2/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5/h6-9H,1-5H3/q+1

59-99-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name neostigmine

1.2 Other means of identification

Product number -
Other names Prostigmin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:59-99-4 SDS

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59-99-4Downstream Products

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