59018-48-3Relevant academic research and scientific papers
3-Alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides as ATP-sensitive potassium channel openers: Effect of 6,7-disubstitution on potency and tissue selectivity
De Tullio, Pascal,Boverie, Stéphane,Becker, Bénédicte,Antoine, Marie-Hélène,Nguyen, Quynh-Anh,Francotte, Pierre,Counerotte, Stéphane,Sebille, Sophie,Pirotte, Bernard,Lebrun, Philippe
, p. 4990 - 5000 (2007/10/03)
A series of 6,7-disubstituted 4H-1,2,4-benzothiadiazine 1,1-dioxides bearing a short alkylamino side chain in the 3-position were synthesized. These compounds were tested on rat pancreatic islets and on rat aorta rings. In vitro data indicated that in mos
