59023-30-2

Basic information

• Product Name: 1-methylimidazol-2-ylmethyldiphenylmethanol
• Synonyms: 1-methylimidazol-2-ylmethyldiphenylmethanol
• CAS NO: 59023-30-2
• Molecular Weight: 278.354
• Mol File: 59023-30-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-methylimidazol-2-ylmethyldiphenylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methylimidazol-2-ylmethyldiphenylmethanol(59023-30-2)
• EPA Substance Registry System: 1-methylimidazol-2-ylmethyldiphenylmethanol(59023-30-2)

Safety Data

• Hazardous Substances Data: 59023-30-2(Hazardous Substances Data)

Upstream product

• 119-61-9 benzophenone 
• 86051-74-3 1,2-dimethyl-5-trimethylstannylimidazole 
• 1739-84-0 1,2-dimethyl-1H-imidazole 

Relevant articles and documents

Reactions of 1,2-Dimethylimidazole, Particularly its Metallation

A re-examination of the metallation of 1,2-dimethylimidazole has shown that, after quenching of reaction mixtures with suitable reagents, single products may arise from substitution either in the 2-methyl group or in the 5-position or mixtures of both products may arise, depending on the metallating reagent, solvent, and reaction conditions. 1,2-Dimethylimidazol-5-yl-lithium was prepared by reaction of 1,2-dimethyl-5-trimethylstannylimidazole (13) with n-butyl-lithium in tetrahydrofuran at -100 deg C.The corresponding 5-trimethylsilyl compounds (12) was metallated by n-butyl-lithium exclusively in the 2-methyl group. 1,2-Dimethylimidazol-5-yl-lithium was shown to undergo transmetallation reactions at temperatures higher than -100 deg C.An improved procedure is given for the synthesis of 1,2-dimethylimidazole-5-carbaldehyde via hydroxymethylation of 1,2-dimethylimidazole and oxidation of the 5-hydroxymethyl group with nitric acid.