59034-30-9

Upstream product

• 551-16-6 6-Aminopenicillanic Acid 
• 20425-27-8 (2S,5R,6R)-6-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 
• 22509-74-6 N-ethoxycarbonylphthalimide 
• 182268-32-2 benzyl (2S)-2-[(3R,4S)-4-chloro-3-phthalimido-2-oxazetidin-1-yl]-2-(1-chlorothio-1-methylethyl)-acetate 

Downstream Products

• 182268-33-3 benzyl (-)-(2S,4S,5S,6R)-3,3-dimethyl-7-oxo-6-phthalimido-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide 
• 1316164-03-0 2-[(2S,5S,6R)-2-(benzyloxycarbonyl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-6-ylcarbamoyl]benzoic acid 
• 1316164-09-6 benzyl (2S,5S,6R)-3,3-dimethyl-7-oxo-6-phthalisoimido-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 
• 1316164-12-1 benzyl (2S,5S,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 
• 1316164-17-6 benzyl (2S,5S,6R)-6-[(N-decanoyl-L-prolyl-L-threonyl-L-alanyl-L-asparaginyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]-heptane-2-carboxylate 
• 182268-37-7 benzyl (-)-(6S,7S)-3-methyl-7-(4-nitrobenzenesulfenamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 
• 182186-39-6 benzyl (-)-(6S,7R)-3-methyl-7-(4-nitrobenzenesulfenamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 
• 182268-29-7 benzyl (-)-(6S,7S)-3-methyl-8-oxo-7-phenoxyacetamido-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 
• 182268-35-5 benzyl (-)-(6S,7S)-3-methyl-7-(4-nitrobenzylideneamino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 
• 182186-38-5 benzyl (-)-(6S,7R)-3-methyl-8-oxo-7-phthalimido-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 
• 182186-48-7 benzyl (-)-(6S,7S)-3-methyl-8-oxo-5-thia-7-(4-toluenesulfenamido)-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 
• 182268-28-6 benzyl (-)-(6S,7S)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 
• 182268-34-4 benzyl (-)-(6S,7R)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 
• 182186-42-1 benzyl (-)-(6S,7R)-3-methyl-7-[[(4-nitrophenyl)thio]imino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 

Relevant academic research and scientific papers

Asymmetric synthesis of new β-lactam lipopeptides as bacterial signal peptidase i inhibitors

The transmembrane bacterial enzyme, signal peptidase I, is recognized as being a promising target for reducing the emergence of drug resistance. The asymmetric synthesis and the biological evaluation of original β-lactam lipopeptides have been performed t

Syntheses of (6S)-cephalosporins from 6-aminopenicillanic acid

Two practical routes to (6S,7S)-cephalosporins from 6-aminopenicillanic acid (6-APA) are described. In the first, 6-APA was converted to (2S,4S,5S,6S)-penicillin sulfoxide 49, which underwent Morin ring expansion to a protected (6S,7S)-cephem 50. In the s

Syntheses of (6S,7S)- and (6S,7R)-deacetoxycephalosporanic acids from 6-aminopenicillanic acid

Two practical (i.e. applicable to multigram scale synthesis) approaches to (6S,7S)-cephalosporins (i.e. the enantiomers of naturally occuring cephalosporins) and the (6S)-epimers of cephalosporins from readily available (2S,5R,6R)-6-aminopenicillanic acid