590353-10-9

Usage

Uses

Used in Pharmaceutical and Biomedical Research:
ART-CHEM-BB B018041 is used as a research tool for investigating the effects of indole acetic acid derivatives on biological processes. Its potential anti-inflammatory and anti-cancer properties make it of interest for further exploration in the pharmaceutical and biomedical fields.
Used in Chemical Compound Development:
ART-CHEM-BB B018041 is also utilized in the development of new chemical compounds with potential therapeutic applications, contributing to the advancement of medicine and healthcare.

InChI:InChI=1/C13H21N3S/c1-2-10-16-12(14-15-13(16)17)9-8-11-6-4-3-5-7-11/h2,11H,1,3-10H2,(H,15,17)

Upstream product

• 81975-20-4 β-Cyclohexylpropionic acid hydrazide 
• 20681-51-0 methyl 3-cyclohexylpropionate 
• 701-97-3 cyclohexanepropionic acid 
• 590353-08-5 N-allyl-2-(3-cyclohexylpropanoyl)hydrazinecarbothioamide 

Relevant academic research and scientific papers

Synthesis of novel 3-cyclohexylpropanoic acid-derived nitrogen heterocyclic compounds and their evaluation for tuberculostatic activity

A series of novel 3-cyclohexylpropanoic acid derivatives and 3-cyclohexylpropanoic acid-derived nitrogen heterocyclic compounds (1-8) have been synthesized and evaluated for tuberculostatic activity. Compounds 1a, 1c, 1e and 1f bearing benzimidazole or benzimidazole-like systems showed the most potent tuberculostatic activity against Mycobacterium tuberculosis strains with MIC values ranging from 1.5 to 12.5 μg/mL. More importantly 1a (6-chloro-2-(2-cyclohexylethyl)-4-nitro-1H-benzo[d]imidazole) and 1f (2-(2-cyclohexylethyl)-1H-imidazo[4,5-b]phenazine) appeared selective for M. tuberculosis as compared with eukaryotic cells (human fibroblasts), and other antimicrobial strains. These compounds may thus represent a novel, selective class of antitubercular agents. Additionally compound 1a stimulated type I collagen output by fibroblasts, in vitro.