590356-43-7

Basic information

• Product Name: 2-(2-bromophenoxy)propionic acid methyl ester
• Synonyms: 2-(2-bromophenoxy)propionic acid methyl ester
• CAS NO: 590356-43-7
• Molecular Weight: 259.1
• Mol File: 590356-43-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-(2-bromophenoxy)propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-bromophenoxy)propionic acid methyl ester(590356-43-7)
• EPA Substance Registry System: 2-(2-bromophenoxy)propionic acid methyl ester(590356-43-7)

Safety Data

• Hazardous Substances Data: 590356-43-7(Hazardous Substances Data)

Upstream product

• 5445-17-0 Methyl 2-bromopropionate 
• 95-56-7 2-hydroxybromobenzene 
• 547-64-8 methyl lactate 
• 600-22-6 pyruvic acid methyl ester 

Downstream Products

• 4265-25-2 2-methylbenzofuran 
• 819071-86-8 2-(2-thiophen-3-ylphenoxy)propionic acid methyl ester 

Relevant articles and documents

SPIROCYCLIC TETRAHYDROQUINAZOLINES

Provided are compounds represented by Formula I, wherein R3, A, A1, A2, A3, E, E1, E2, L, Q, Z, and (aa) are as defined in the specification, and the pharmaceutically acceptable salts and solvates thereof. Compounds of Formula (I) are KRAS inhibitors and are thus useful to treat cancer and other diseases.

Pd-catalyzed intramolecular Heck reaction for the synthesis of 2-methylbenzofurans

A new strategy for the synthesis of 2-Methylbenzofurans via the intramolecular Heck reaction has been developed. This efficient palladium-catalyzed system showed good catalytic activity. Various substituted 2-methylbenzofurans could be afforded in good to excellent yields.

Might the observed α2A-adrenoreceptor agonism or antagonism of allyphenyline analogues be ascribed to different molecular conformations?

We recently reported that the α2-adrenoreceptor (AR) ligand allyphenyline (9) significantly enhanced morphine analgesia (due to its α2C-AR agonism), was devoid of sedative side effects (due to its α2A-AR antagonism), preve