590367-82-1Relevant academic research and scientific papers
Synthesis and in vitro antimicrobial evaluation of 5-(1-methyl-5-nitro-2-imidazolyl)-4H-1,2,4-triazoles
Shafiee, Abbas,Sayadi, Abolfazl,Roozbahani, Marjan Hosseini,Foroumadi, Alireza,Kamal, Fatemeh
, p. 495 - 499 (2007/10/03)
The increasing clinical importance of drug-resistant pathogens has lent additional urgency to antimicrobial research. Various 5-(1-methyl-5-nitro-2-imidazolyl)-4H-1,2,4-triazoles (4a-6f) were synthesized and tested in vitro for their antibacterial and antifungal activities. Compounds 4a and 4b exhibited significant effects against Bacillus subtilis at MIC ranges of 0.5-1 μg/mL and moderate effects against Staphylococcus aureus.
