590371-95-2 Usage
Uses
Used in Medicinal Chemistry:
2-Bromo-3-(trifluoromethyl)quinoline is used as a chemical intermediate for the synthesis of various pharmaceutical compounds due to its unique structure and potential biological activities. Its presence in quinoline derivatives suggests that it may contribute to the development of new drugs with antimalarial, antibacterial, antifungal, anticancer, anti-inflammatory, and analgesic properties.
Used in Research and Development:
In the field of pharmaceutical research, 2-bromo-3-(trifluoromethyl)quinoline serves as a valuable compound for exploring its potential applications and understanding its interactions with biological systems. This can lead to the discovery of new therapeutic agents and a better comprehension of the underlying mechanisms of action.
Used in Drug Synthesis:
2-Bromo-3-(trifluoromethyl)quinoline is used as a key building block in the synthesis of complex drug molecules. Its unique structural features, including the bromine atom and trifluoromethyl group, can be exploited to create novel compounds with improved pharmacological properties, such as increased potency, selectivity, or bioavailability.
Used in Chemical Synthesis:
Beyond its potential applications in medicinal chemistry, 2-bromo-3-(trifluoromethyl)quinoline can also be utilized in the synthesis of other organic compounds, such as dyes, agrochemicals, or materials with specific properties. Its versatility as a synthetic intermediate opens up opportunities for its use in various chemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 590371-95-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,9,0,3,7 and 1 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 590371-95:
(8*5)+(7*9)+(6*0)+(5*3)+(4*7)+(3*1)+(2*9)+(1*5)=172
172 % 10 = 2
So 590371-95-2 is a valid CAS Registry Number.
InChI:InChI=1S/C10H5BrF3N/c11-9-7(10(12,13)14)5-6-3-1-2-4-8(6)15-9/h1-5H
590371-95-2Relevant academic research and scientific papers
Recommendable routes to trifluoromethyl-substituted pyridine- and quinolinecarboxylic acids
Cottet, Fabrice,Marull, Marc,Lefebvre, Olivier,Schlosser, Manfred
, p. 1559 - 1568 (2007/10/03)
As part of a case study, rational strategies for the preparation of all ten 2-, 3-, or 4-pyridinecarboxylic acids and all nine 2-, 3-, 4-, or 8-quinolinecarboxylic acids bearing trifluoromethyl substituents at the 2-, 3-, or 4-position were elaborated. The trifluoromethyl group, if not already present in the precursor, was introduced either by the deoxygenative fluorination of suitable carboxylic acids with sulfur tetrafluoride or by the displacement of ring-bound bromine or iodine by trifluoromethylcopper generated in situ. The carboxy function was produced by treatment of organolithium or organomagnesium intermediates, products of halogen/metal or hydrogen/ metal permutation, with carbon dioxide. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).
