5904-89-2

Basic information

• Product Name: 2-[(2-ISOPROPYLPHENOXY)METHYL]OXIRANE
• Synonyms: 2-[(2-propan-2-ylphenoxy)methyl]oxirane
• CAS NO: 5904-89-2
• Molecular Formula: C₁₂H₁₆O₂
• Molecular Weight: 192.25
• Mol File: 5904-89-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 286.1°Cat760mmHg
• Flash Point: 111.1°C
• Appearance: /
• Density: 1.045g/cm³
• Vapor Pressure: 0.00464mmHg at 25°C
• Refractive Index: 1.52
• CAS DataBase Reference: 2-[(2-ISOPROPYLPHENOXY)METHYL]OXIRANE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(2-ISOPROPYLPHENOXY)METHYL]OXIRANE(5904-89-2)
• EPA Substance Registry System: 2-[(2-ISOPROPYLPHENOXY)METHYL]OXIRANE(5904-89-2)

Safety Data

• Hazardous Substances Data: 5904-89-2(Hazardous Substances Data)

Usage

Type of compound

epoxide

Usage

production of polymers, building block in organic synthesis

Appearance

colorless to pale yellow liquid

Odor

faint

Stability

relatively stable under normal conditions

Reactivity

ability to undergo ring-opening reactions

Toxicity

toxic, requires careful handling and proper safety protocols.

InChI:InChI=1/C12H16O2/c1-9(2)11-5-3-4-6-12(11)14-8-10-7-13-10/h3-6,9-10H,7-8H2,1-2H3/t10-/m1/s1

Upstream product

• 88-69-7 2-(1-methylethyl)phenol 
• 106-89-8 epichlorohydrin 
• 3132-64-7 1,2-Epoxy-3-bromopropane 

Downstream Products

• 1005152-69-1 C₁₈H₂₉NO₃ 
• 1254940-29-8 C₂₉H₃₄N₄O₂S 
• 129975-58-2 2-(3,4-Dimethoxy-phenyl)-5-{[2-hydroxy-3-(2-isopropyl-phenoxy)-propyl]-methyl-amino}-2-isopropyl-pentanenitrile 

Relevant articles and documents

Substituted diaryl compound and preparation method and application thereof

The invention relates to the field of medicinal chemistry, in particular to a substituted diaryl compound (I). The preparation method comprises the following steps: medicine preparation and medical application thereof. Test results show that the substituted diaryl compound has a good inhibition effect on human lung cancer (A549), human ovarian cancer (SKOV3), human melanoma (A375) and human colon cancer (LOVO) cells. Formula (I):

A facile and efficient method for synthesis of β-iodocarboxylates from terminal epoxides

A facile and efficient method has been developed for synthesis of β-iodocarboxylates in the presences of Ph3P/I2. Starting from epoxides, a series of β-iodocarboxylate compounds can be directly obtained in toluene media with excellent yields. Moreover, the method was successfully applied for the late-stage modification of natural products, such as isosteviol and vincamine derivatives, achieving the corresponding β-iodocarboxylates in good yields.

ANALGESIC THAT BINDS FILAMIN A

A compound, composition and method are disclosed that can provide analgesia. A contemplated compound has a structure that corresponds to Formula A, wherein A, B, X, R1, R2, R7 and R8, and the dashed lines are defined within.