590417-28-0

Basic information

• Product Name: Boronic acid, (5-hydroxy-2-naphthalenyl)- (9CI)
• Synonyms: Boronic acid, (5-hydroxy-2-naphthalenyl)- (9CI)
• CAS NO: 590417-28-0
• Molecular Formula: C₁₀H₉BO₃
• Molecular Weight: 187.98766
• Product Categories: BORONICACID
• Mol File: 590417-28-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Boronic acid, (5-hydroxy-2-naphthalenyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Boronic acid, (5-hydroxy-2-naphthalenyl)- (9CI)(590417-28-0)
• EPA Substance Registry System: Boronic acid, (5-hydroxy-2-naphthalenyl)- (9CI)(590417-28-0)

Safety Data

• Hazardous Substances Data: 590417-28-0(Hazardous Substances Data)

Upstream product

• 128542-53-0 2-iodo-5-hydroxynaphthalene 

Downstream Products

• 590411-18-0 methyl 3-[4-cyclopentylmethyloxy-3-(5-hydroxynaphthalen-2-yl)phenyl]propionate 

Relevant articles and documents

Singlet oxygen carrier for inhibiting beta-amyloid protein aggregation as well as preparation method and application thereof

The invention discloses a singlet oxygen carrier for inhibiting beta-amyloid protein aggregation as well as a preparation method and application thereof, which belongs to the technical field of biological medicines. The singlet oxygen carrier for inhibiting beta-amyloid protein aggregation contains two functional groups, namely a benzothiazole group and a singlet oxygen carrier. The benzothiazole group can be selectively combined with the beta-amyloid protein, so that the targeting property of the system is improved, the aggregation of the beta-amyloid protein is inhibited, and the neurotoxicity caused by the beta-amyloid protein is reduced. The endoperoxide in the system can release singlet oxygen under a certain condition, and the singlet oxygen can oxidize the beta-amyloid protein, so that the aggregation of the beta-amyloid protein is further limited, and the toxicity is reduced. The carrier has dual inhibition effects on beta-amyloid protein, and has application potentials of treating related diseases caused by beta-amyloid protein aggregation and relieving Alzheimer's disease and other diseases.

Substituted phenylalkanoic acid derivatives and use thereof

A compound represented by the formula (I) or a salt thereof: wherein n represents an integer of 1 to 3, R represents an alkyl group having 3 to 8 carbon atoms, a group represented by the following formula: R1(CH2)k— (wherein k represents 0 or an integer of 1 to 3; R1 represents a saturated cyclic alkyl group having 3 to 7 carbon atoms or a saturated condensed cyclic alkyl group having 6 to 8 carbon atoms, and the group R1 may be substituted with a lower alkyl group having 1 to 4 carbon atoms) and the like, and Ar represents a condensed bicyclic group such as naphthalen-1-yl group, which has suppressing action on prostaglandin and leukotriene production and is useful for prophylactic and/or therapeutic treatment of various inflammatory diseases and the like caused by these lipid mediators.