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5906-30-9

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5906-30-9 Usage

Explanation

1-Piperazinesulfonamide(7CI,8CI,9CI) has a molecular formula of C4H10N2O2S, which indicates the number of carbon, hydrogen, nitrogen, oxygen, and sulfur atoms in the compound.

Explanation

It belongs to the piperazine class of compounds, which is a group of chemical structures that includes a six-membered heterocyclic ring with four carbon atoms and two nitrogen atoms.

Explanation

1-Piperazinesulfonamide(7CI,8CI,9CI) contains a sulfonamide functional group, which is a chemical group consisting of a sulfur atom double-bonded to an oxygen atom and single-bonded to a nitrogen atom (-SO2NH2).

Explanation

This chemical compound is a white solid, which describes its color and physical state.

Explanation

1-Piperazinesulfonamide(7CI,8CI,9CI) is soluble in water, meaning it can dissolve in aqueous solutions to form a homogeneous mixture.

Explanation

The compound has various applications in fields such as medicinal chemistry (as a building block for synthesizing pharmaceuticals and biologically active molecules), corrosion inhibition, pesticide production, and the manufacture of dyes and pigments.

Explanation

1-Piperazinesulfonamide(7CI,8CI,9CI) has been studied for its potential as an anticancer and antimicrobial agent, indicating possible future applications in the treatment of cancer and infections.

Piperazine class

Compound class

Sulfonamide functional group

Functional group present

Physical appearance

White solid

Solubility

Soluble in water

Applications

Medicinal chemistry, corrosion inhibition, pesticides, dyes and pigments

Potential therapeutic uses

Anticancer and antimicrobial agent

Check Digit Verification of cas no

The CAS Registry Mumber 5906-30-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,0 and 6 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5906-30:
(6*5)+(5*9)+(4*0)+(3*6)+(2*3)+(1*0)=99
99 % 10 = 9
So 5906-30-9 is a valid CAS Registry Number.
InChI:InChI=1/C21H26F2N4O2/c1-14(2)26(21(29)24-19-9-6-15(22)11-18(19)23)13-20(28)27(16-7-8-16)12-17-5-4-10-25(17)3/h4-6,9-11,14,16H,7-8,12-13H2,1-3H3,(H,24,29)

5906-30-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name piperazine-1-sulfonamide

1.2 Other means of identification

Product number -
Other names 1-Sulfamylpiperazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5906-30-9 SDS

5906-30-9Downstream Products

5906-30-9Relevant articles and documents

DUAL ACTION CARBONIC ANHYDRASE INHIBITORS

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Page/Page column 77, (2015/03/13)

The present invention is directed to novel carbonic anhydrase IX inhibitors comprising a nitroimidazole moiety substituted with a heterocycle or phosphinate and having sulfonamide, sulfamate or sulfamide groups. The present invention is also related to the use of these novel carbonic anhydrase IX inhibitors in cancer treatment, especially radiotherapy and chemotherapy and the use in treatment of infections.

Insertion of an aspartic acid moiety into cyclic pseudopeptides: Synthesis and biological characterization of potent antagonists for the human tachykinin NK-2 receptor

Fedi, Valentina,Altamura, Maria,Balacco, Giuseppe,Canfarini, Franca,Criscuoli, Marco,Giannotti, Danilo,Giolitti, Alessandro,Giuliani, Sandro,Guidi, Antonio,Harmat, Nicholas J. S.,Nannicini, Rossano,Pasqui, Franco,Patacchini, Riccardo,Perrotta, Enzo,Tramontana, Manuela,Triolo, Antonio,Maggi, Carlo Alberto

, p. 6935 - 6947 (2007/10/03)

A new series of monocyclic pseudopeptide tachykinin NK-2 receptor antagonists has been derived from the lead compound MEN11558. A synthesis for these molecules sharing the same intermediate was designed and performed. The replacement of the succinic moiety with an aspartic acid and the functionalization of its amino group with a wide variety of substituents led to very potent and selective NK-2 antagonists. Best results were obtained through the insertion in position 12 of an amino group with R configuration, linked by a short spacer to a saturated nitrogen heterocycle (morpholine, piperidine, or piperazine). The study led to compounds 54 and 57, endowed with high in vivo potency at very low doses and long duration of action in animal models of bronchoconstriction. In particular 54 and 57 completely inhibited NK-2 agonist induced bronchoconstriction in guinea pig after intratracheal administration at subnanomolar doses (ED50 = 0.27 nmol/kg and 0.15 nmol/kg, respectively).

C-Piperazino-pyridine sulfonamides

-

, (2008/06/13)

This invention relates to compounds of the formula: SPC1 Wherein R1 in the 3- or 5-position is preferably a substituted sulfonamido or a carboxamido group whereas R2 in the 2-, 4- or 6-position is preferably an alkyl- or hydroxyalkyl-piperazinyl group. Said compounds may be used as anti-inflammatory and cardiovascular agents.

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