59079-03-7Relevant academic research and scientific papers
4-aryl-2,4-dioxobutanoic acids and their derivatives in reactions with diazoalkanes
Zalesov,Kataev,Pulina,Kovylyaeva
, p. 840 - 844 (2007/10/03)
By treating 4-aryl-2,4-dioxobutanoic acids or their alkyl esters with diazomethane alkyl 4-aryl-2-methoxy-4-oxo-2-butenoates and 1-R-3-aroyl-4-methoxy-4-methoxycarbonyl-4,5-dihydropyrazoles were prepared. O-Alkyl derivatives and substituted pyrazoles were
Pyruvic Acid Dimethylhydrazone. A Synthetic Equivalent of the Pyruvic Acid Dianion
Tapia, Ines,Alcazar, Victoria,Moran, Joaquin R.,Caballero, Cruz,Grande, Manuel
, p. 697 - 700 (2007/10/02)
The pyruvic acid dimethyl hydrazone can be easily prepared in ether.This compound, after deprotonation with alkyllithium, forms a strong nucleophile which on tratment with electrophiles and acidic work up yield α-ketoacids, α-hydroxybutenolides or α,γ-diketoacids.
