59082-21-2Relevant academic research and scientific papers
A simple iron-catalyst for alkenylation of ketones using primary alcohols
Sk, Motahar,Kumar, Ashish,Das, Jagadish,Banerjee, Debasis
, (2020/04/10)
Herein, we developed a simple iron-catalyzed system for the α-alkenylation of ketones using primary alcohols. Such acceptor-less dehydrogenative coupling (ADC) of alcohols resulted in the synthesis of a series of important α,β-unsaturated functionalized ketones, having aryl, heteroaryl, alkyl, nitro, nitrile and trifluoro-methyl, as well as halogen moieties, with excellent yields and selectivity. Initial mechanistic studies, including deuterium labeling experiments, determination of rate and order of the reaction, and quantitative determination of H2 gas, were performed. The overall transformations produce water and dihydrogen as byproducts.
Synthesis of benzo[c]xanthones from 2-benzylidene-1-tetralones by the ultraviolet radiation-mediated tandem reaction
Xu, Wen-Zhi,Huang, Zhi-Tang,Zheng, Qi-Yu
, p. 5606 - 5608 (2008/12/21)
(Chemical Equation Presented) A facile one-pot method to prepare benzo[c]xanthones from readily accessible benzylidene-1-tetralones by the ultraviolet radiation-mediated tandem reaction is reported. The overall transformation presumably involves cis-trans
Solvent-free microwave enhanced synthesis of 2-arylidene-1-tetralones
Mogilaiah,Reddy, G. Randheer,Prashanthi
, p. 1535 - 1536 (2007/10/03)
A rapid and efficient method for the synthesis of 2-arylidene-1-tetralones 2 by the condensation of 1-tetralone 1 with aromatic aldehydes in the presence of p-toluenesulphonic acid (PTSA) in solvent free conditions under microwave irradiation is reported.
Ground- and excited-state properties of some 3,4-dihydro-1-(2-p-substituted benzylidene)naphthalenones: Substituent and environmental effects
Al-Ansari, Ibrahim A. Z.
, p. 687 - 696 (2007/10/03)
Electronic absorption and steady-state fluorescence emission of seven 3,4-dihydro-1-(2-p-substituted benzylidene)naphthalenones (1-7) show sizable solvent dependence. The charge-transfer (CT) absorption maxima of these compounds in various solvents show a
Synthesis of 3,3a-trans/cis-2-phenyl/acetyl-3-aryl-tetrahydroindeno/naphtho-and hexahydrobenzocycloheptapyrazoles as antiimplantation agents
Sinha, Anoop Kumar,Rastogi, Shri Nivas
, p. 684 - 692 (2007/10/02)
Reaction of benzocycloalkanones (1-3 and 24) and araldehydes (4-6) gives the arylideno-alkanones (7-12, 25 and 26) of which 11 and 12 on alkylation and acetylation afford alkyl ethers (13, 14 and 17) and acetates (15 and 16) respectively.Condensation of a
2-Substituted-1-naphthols as potent 5-lipoxygenase inhibitors with topical antiinflammatory activity
Batt,Maynard,Petraitis,Shaw,Galbraith,Harris
, p. 360 - 370 (2007/10/02)
The synthesis, biological evaluation, and structure-activity relationships of a series of 1-naphthols bearing carbon substituents at the 2-position are described. These compounds are potent inhibitors of the 5-lipoxygenase from RBL-1 cells and also inhibi
Heterocycles. Part VIII. Synthesis of New Substituted Benzindazoles
El-Rayyes, N. R.,Al-Jawhary, A.
, p. 135 - 140 (2007/10/02)
Aryl aldehydes I reacted with α-tetralone to give the corresponding 2-arylidene-1-tetralone II.Condensation of the latter chalcones with hydrazine, methylhydrazine and phenylhydrazine produced the corresponding benzoindazoles III, V and VI respectively
