5909-25-1

Basic information

• Product Name: ethyl 2,4-bis(methylsulfanyl)pyrimidine-5-carboxylate
• Synonyms: 5-Pyrimidinecarboxylic acid, 2,4-bis(methylthio)-, ethyl ester
• CAS NO: 5909-25-1
• Molecular Formula: C₉H₁₂N₂O₂S₂
• Molecular Weight: 244.3338
• Mol File: 5909-25-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 382.1°C at 760 mmHg
• Flash Point: 184.9°C
• Density: 1.29g/cm³
• Vapor Pressure: 4.84E-06mmHg at 25°C
• Refractive Index: 1.586
• CAS DataBase Reference: ethyl 2,4-bis(methylsulfanyl)pyrimidine-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2,4-bis(methylsulfanyl)pyrimidine-5-carboxylate(5909-25-1)
• EPA Substance Registry System: ethyl 2,4-bis(methylsulfanyl)pyrimidine-5-carboxylate(5909-25-1)

Safety Data

• Hazardous Substances Data: 5909-25-1(Hazardous Substances Data)

Upstream product

• 5909-24-0 4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester 
• 5188-07-8 sodium thiomethoxide 

Downstream Products

• 148550-51-0 ethyl 2-(methylsulfonyl)pyrimidine-5-carboxylate 

Relevant articles and documents

cGAS ANTAGONIST COMPOUNDS

Disclosed are novel compounds of Formula (I) that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS

The invention relates to inhibitors of the phosphodiesterase 4 (PDE4) enzyme. More particularly, the invention relates to compounds that are derivatives of 1-phenyl-2-pyridinyl alkyl alcohols, methods of preparing such compounds, compositions containing them and therapeutic use thereof.