Albaspidin AP is a marine natural product alkaloid derived from the sponge Alibasis sp. It is characterized by its potent cytotoxic and antiproliferative activities against a wide range of cancer cell lines. Albaspidin AP induces apoptosis in cancer cells by disrupting microtubule assembly and inhibiting tubulin polymerization. Furthermore, it exhibits anti-inflammatory properties by suppressing the production of nitric oxide and pro-inflammatory cytokines. Due to its unique chemical structure and potent biological activities, Albaspidin AP holds promise as a lead compound for the development of novel anticancer drugs.
59092-91-0
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Basic information
- Product Name: Albaspidin AP
- Synonyms: Albaspidin AP;2,5-Cyclohexadien-1-one,2-[(5-acetyl-2,4- dihydroxy-3,3-dimethyl-6-oxo-1,4-cyclohexadien- 1-yl)methyl]-3,5-dihydroxy-4,4- dimethyl-6-(1-oxopropyl)-
- CAS NO:59092-91-0
- Molecular Formula: C22H26O8
- Molecular Weight: 418.43704
- EINECS: N/A
- Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
- Mol File: 59092-91-0.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 654.8±55.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.392±0.06 g/cm3 (20 ºC 760 Torr)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 4.50±1.00(Predicted)
- CAS DataBase Reference: Albaspidin AP(CAS DataBase Reference)
- NIST Chemistry Reference: Albaspidin AP(59092-91-0)
- EPA Substance Registry System: Albaspidin AP(59092-91-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 59092-91-0(Hazardous Substances Data)
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59092-91-0 Usage
Uses
Used in Pharmaceutical Industry:Albaspidin AP is used as a potential anticancer agent for its ability to induce apoptosis in cancer cells by disrupting microtubule assembly and inhibiting tubulin polymerization. Its broad-spectrum cytotoxic and antiproliferative activities make it a valuable candidate for the development of new cancer treatments.
Used in Anti-inflammatory Applications:
Albaspidin AP is utilized as an anti-inflammatory agent due to its capacity to inhibit the production of nitric oxide and pro-inflammatory cytokines. This property can be beneficial in managing inflammation-related conditions and diseases.
Used in Drug Development:
Albaspidin AP serves as a promising lead compound for the development of innovative anticancer drugs. Its unique chemical structure and potent biological activities offer opportunities for the creation of new therapeutic agents with improved efficacy and reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 59092-91-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,0,9 and 2 respectively; the second part has 2 digits, 9 and 1 respectively.Calculate Digit Verification of CAS Registry Number 59092-91:
(7*5)+(6*9)+(5*0)+(4*9)+(3*2)+(2*9)+(1*1)=150
150 % 10 = 0
So 59092-91-0 is a valid CAS Registry Number.
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59092-91-0Downstream Products
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Albaspidin AP
