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6-Fluorouracil, also known as 5-FU, is a synthetic chemotherapeutic agent that functions as an antimetabolite, being a fluorinated analog of the nucleoside uracil. It possesses the ability to inhibit DNA synthesis and cell proliferation by disrupting the metabolism of RNA and DNA, making it a significant component in cancer treatment regimens.

591-36-6

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591-36-6 Usage

Uses

Used in Oncology:
6-Fluorouracil is utilized as an anticancer drug for the treatment of various malignancies, such as breast, colon, and skin cancers. It operates by integrating into the DNA and RNA of cancer cells, thereby hindering their replication and growth. This medication is often administered intravenously or topically and is frequently combined with other chemotherapy agents to enhance the therapeutic effect and manage cancer more effectively.
Used in Combination Therapy:
In the field of oncology, 6-Fluorouracil is used as a component of combination therapy to increase the effectiveness of cancer treatment. The synergistic action with other chemotherapeutic drugs allows for a more potent attack on cancer cells while potentially reducing the dosage of each drug, which can help in minimizing side effects.
However, the use of 6-Fluorouracil requires careful patient monitoring due to its potential side effects, which can include nausea, vomiting, diarrhea, and bone marrow damage. Healthcare professionals must closely observe patients to ensure the safe and effective administration of this medication.

Check Digit Verification of cas no

The CAS Registry Mumber 591-36-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,9 and 1 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 591-36:
(5*5)+(4*9)+(3*1)+(2*3)+(1*6)=76
76 % 10 = 6
So 591-36-6 is a valid CAS Registry Number.
InChI:InChI=1/C4H3FN2O2/c5-2-1-3(8)7-4(9)6-2/h1H,(H2,6,7,8,9)

591-36-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-Fluoropyrimidine-2,4(1H,3H)-dione

1.2 Other means of identification

Product number -
Other names 6-fluoro-1H-pyrimidine-2,4-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:591-36-6 SDS

591-36-6Upstream product

591-36-6Downstream Products

591-36-6Relevant academic research and scientific papers

PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS

-

, (2010/03/02)

The invention relates to a process for straightening keratin fibres, comprising: (i) a step in which a straightening composition containing at least two denaturing agents is applied to the keratin fibres, (ii) a step in which the temperature of the keratin fibres is raised, using a heating means, to a temperature of between 110 and 250° C.

UBER SYNTHESEN VON DIFLUORAMINOPYRIMIDINEN

Meinert, H.,Gross, U.,Rudiger, St.

, p. 355 - 362 (2007/10/02)

The synthese of difluoroaminopyrimidines are reported.By direct fluorination of amino derivatives the corresponding difluoroamino-compounds and other fluorinated products are formed.In the case of the alkylation of difluoroamine by protonated pyrimidines the formation of difluoroamino-compounds is discussed.

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