59115-82-1

Basic information

• Product Name: 2-Butanone, 3-(4-methylphenyl)-
• CAS NO: 59115-82-1
• Molecular Formula: C11H14O
• Molecular Weight: 162.232
• Mol File: 59115-82-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-Butanone, 3-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanone, 3-(4-methylphenyl)-(59115-82-1)
• EPA Substance Registry System: 2-Butanone, 3-(4-methylphenyl)-(59115-82-1)

Safety Data

• Hazardous Substances Data: 59115-82-1(Hazardous Substances Data)

Upstream product

• 2096-86-8 p-Tolylaceton 
• 74-88-4 methyl iodide 
• 1758-32-3 2,3-epoxybutane 
• 106-38-7 para-bromotoluene 
• 106-43-4 para-chlorotoluene 
• 78-93-3 butanone 
• 6213-85-0 Methyl 4-brosylate 
• 598-32-3 2-hydroxy-3-butene 
• 624-31-7 4-tolyl iodide 
• 108323-49-5 p-Methyl-α-methyl-epoxyzimtsaeure-methylester 
• 143918-73-4 3-Oxo-2-p-tolyl-butyric acid methyl ester 
• 104-87-0 4-methyl-benzaldehyde 
• 40119-34-4 2-methyl-2-(4-methylphenyl)propionitrile 
• 32454-12-9 2-methyl-2-(4-methylphenyl)propionaldehyde 

Downstream Products

• 1309381-12-1 3-(p-methylphenyl)-2-butanone oxime 
• 1262155-49-6 C₂₁H₂₁NO₃S 
• 1309380-90-2 C₁₈H₂₁NO₄S 
• 536-50-5 CH₃C₆H₄CH(CH₃)OH 
• 122-00-9 para-methylacetophenone 
• 1372209-58-9 N-methyl-2-(p-tolyl)propanamide 
• 91633-31-7 1-(para-methylphenyl)-1-azidoethane 
• 63099-36-5 Trifluoro-methanesulfonic acid (E)-1-methyl-2-p-tolyl-propenyl ester 
• 63099-42-3 Trifluoro-methanesulfonic acid (Z)-1-methyl-2-p-tolyl-propenyl ester 
• 63099-35-4 Trifluoro-methanesulfonic acid (E)-2-(4-methoxy-phenyl)-1-methyl-propenyl ester 
• 34815-72-0 erythro-2-p-tolylbutan-3-ol 
• 34815-72-0 threo-2-p-tolylbutan-3-ol 

Relevant articles and documents

Benzyl C–O and C–N Bond Construction via C–C Bond Dissociation of Oxime Ester under Visible Light Irradiation

A photoredox benzyl activation was developed via formidable C(sp3)–C(sp3) bond dissociation of 1-aryl acetone oxime esters, which were easily prepared from benzyl ketones. Further coupling with O- and N- nucleophiles successfully forged important benzyl ether and amines derivatives in one pot. In this process, different substitutions on oxime esters were found compatible and various primary and secondary alcohols and amines, as well as amides showed good performance as nucleophiles. Mechanistic studies by control experiments, electrochemical measurements and in-situ NMR spectra proposed a N–O bond interruption/C–C bond fragmentation/oxidation sequence to provide the key cation intermediate for the next electrophilic SN process. The features of mild condition, short reaction time and broad substrate scope made this new strategy much promising in the transformation of benzyl compounds, which might be valuable in last-stage functionalizations.

Regioselective 1,2-Diol Rearrangement by Controlling the Loading of BF3·Et2O and Its Application to the Synthesis of Related Nor-Sesquiterene- and Sesquiterene-Type Marine Natural Products

The regiocontrolled rearrangement of 1,2-diols has been achieved by controlling the loading of BF3·Et2O. Its applicability is showcased by the divergent synthesis of austrodoral, austrodoric acid, and 8-epi-11-nordriman-9-one, as well as a formal synthesis of siphonodictyal B and liphagal. A new light is shed on piancol-type rearrangements that will be useful in diversity-oriented synthesis of related natural products.

Origin of regioselectivity in the reactions of nitronate and enolate ambident anions

The reactions of nitronates of ring-substituted phenylnitromethanes and enolates of ring-substituted 1-phenyl-2-propanones with MeOBs gave exclusively the O-methylated and C-methylated products, respectively. DFT calculations suggested that two factors, n