59120-85-3Relevant academic research and scientific papers
Formation of dimers of some 2-substituted indan-1-one derivatives during base-mediated cross-aldol condensation
Narang, Gaurav,Jindal, Dharam Paul,Jit, Birinder,Bansal, Ranju,Potter, Brian S.,Palmer, Rex A.
, p. 258 - 264 (2006)
Unexpected dimers of some 2-substituted indan-1-one derivatives were isolated during aldol condensation of indan-1-one with various aldehydes in the presence of KOH (see Scheme). Monomeric products, usually expected from aldol condensation, further underw
Catalytic enantioselective cascade Michael/cyclization reaction of 3-isothiocyanato oxindoles with exocyclic α,β-unsaturated ketones: En route to 3,2′-pyrrolidinyl bispirooxindoles
Kayal, Satavisha,Mukherjee, Santanu
supporting information, p. 10175 - 10179 (2016/11/17)
Cascade Michael/cyclization reactions between 3-isothiocyanato oxindoles and exocyclic α,β-unsaturated ketones are shown to proceed efficiently in the presence of a quinine-derived tertiary amino-squaramide catalyst and furnish 3,2′-pyrrolidinyl bispirooxindoles containing two spiro-quaternary and three contiguous stereocenters as a single diastereomer with excellent enantioselectivities (up to 99:1 er).
