591208-37-6

Basic information

• Product Name: L-Alanine, 1-[(phenylmethoxy)carbonyl]-L-prolyl-3-cyclohexyl-, methyl ester
• CAS NO: 591208-37-6
• Molecular Formula: C23H32N2O5
• Molecular Weight: 416.517
• Mol File: 591208-37-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Alanine, 1-[(phenylmethoxy)carbonyl]-L-prolyl-3-cyclohexyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Alanine, 1-[(phenylmethoxy)carbonyl]-L-prolyl-3-cyclohexyl-, methyl ester(591208-37-6)
• EPA Substance Registry System: L-Alanine, 1-[(phenylmethoxy)carbonyl]-L-prolyl-3-cyclohexyl-, methyl ester(591208-37-6)

Safety Data

• Hazardous Substances Data: 591208-37-6(Hazardous Substances Data)

Upstream product

• 17193-39-4 methyl 3-cyclohexyl-L-alaninate hydrochloride 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 

Downstream Products

• 591208-39-8 (S,S)-N-(4-dimethoxymethyl-benzoyl)proline-cyclohexylalanine carboxylic acid hydrazide 
• 591208-38-7 (S,S)-N-(4-dimethoxymethyl-benzoyl)proline-cyclohexylalanine methyl ester 
• 592521-10-3 (S)-3-Cyclohexyl-2-[((S)-pyrrolidine-2-carbonyl)-amino]-propionic acid methyl ester 

Relevant articles and documents

Metal-ion induced amplification of three receptors from dynamic combinatorial libraries of peptide-hydrazones

Three building blocks of general structure (MeO)2CH-aromatic linker-Pro-amino acid-NHNH2 have been prepared and tested in acid-catalysed dynamic combinatorial libraries. Exposure of these libraries to LiI and NaI led to the amplification of three macrocyclic pseudopeptide receptors. The receptors were isolated and their interactions with LiI and NaI were analysed using NMR, IR and ITC. Binding of the metal ions to the receptors is invariably entropy-driven. Nevertheless, all receptors were found to be flexible with substantial conformational rearrangements accompanying guest binding. This type of receptor is extremely difficult to access through rational design and the fact that dynamic combinatorial chemistry allows facile access to these challenging molecules underlines the power of the dynamic approach.