591210-45-6Relevant articles and documents
Exploration of novel thiobarbituric acid-, rhodanine- and thiohydantoin-based HIV-1 integrase inhibitors
Rajamaki, Suvi,Innitzer, Anna,Falciani, Chiara,Tintori, Cristina,Christ, Frauke,Witvrouw, Myriam,Debyser, Zeger,Massa, Silvio,Botta, Maurizio
scheme or table, p. 3615 - 3618 (2010/03/31)
A novel compound inhibiting HIV-1 integrase has been identified by means of virtual screening techniques. A small family of structurally related molecules has been synthesized and biologically evaluated with some of the compounds possessing micromolar act