59169-66-3 Usage
Chemical compound
6-chloro-N-phenylquinazolin-4-amine
Family
Quinazolin-4-amine
Derivative of
Quinazoline (a bicyclic organic compound)
Structure
Contains a chlorine atom and a phenyl group
Potential applications
Medicinal chemistry
Biological activities
May have biological activities and pharmacological properties
Value
Valuable entity for drug discovery and development
Molecular structure
Promising lead compound for design and synthesis of new pharmaceuticals
Ongoing research
Exploration of potential therapeutic applications and elucidation of chemical properties and biological effects.
Check Digit Verification of cas no
The CAS Registry Mumber 59169-66-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,1,6 and 9 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 59169-66:
(7*5)+(6*9)+(5*1)+(4*6)+(3*9)+(2*6)+(1*6)=163
163 % 10 = 3
So 59169-66-3 is a valid CAS Registry Number.
59169-66-3Relevant articles and documents
PRODUCTION OF INDUCED PLURIPOTENT STEM CELLS
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Page/Page column 60-61, (2012/06/30)
The present disclosure relates to methods and compositions that improve the in vitro production of induced pluripotent stem cells through the use of compounds that promote degradation of p53. The disclosure also relates to compositions and methods for the treatment of cancer, pancreatitis and intracellular pathogens.
Discovery and SAR of 6-substituted-4-anilinoquinazolines as non-competitive antagonists of mGlu5
Felts, Andrew S.,Saleh, Sam A.,Le, Uyen,Rodriguez, Alice L.,Weaver, C. David,Conn, P. Jeffrey,Lindsley, Craig W.,Emmitte, Kyle A.
scheme or table, p. 6623 - 6626 (2010/06/12)
A high-throughput cell-based screen identified a series of 6-substituted-4-anilinoquinazolines as non-competitive antagonists of metabotropic glutamate receptor 5 (mGlu5). This Letter describes the SAR of this series and the profile of selected