59208-47-8Relevant academic research and scientific papers
RAD51 INHIBITORS
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Page/Page column 221-222, (2020/09/27)
This application is directed to inhibitors of RAD51 represented by the following structural formula, (I), and methods for their use, such as to treat cancer, autoimmune diseases, immune deficiencies, or neurodegenerative diseases.
SPIROCHROMANONE DERIVATIVES AS ACETYL COENZYME A CARBOXYLASE (ACC) INHIBITORS
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Page/Page column 105, (2008/06/13)
The invention relates to a compound of a formula (I): , or a pharmaceutically acceptable salt or ester thereof, useful as a therapeutic agent for various ACC-related disorders.
Synthesis and hypolipidemic activity of N-substituted phthalimides. Part V
Sena, Vera L.M.,Srivastava, Rajendra M.,Silva, Ricardo O.,Lima, Vera L.M.
, p. 1283 - 1288 (2007/10/03)
A series of N-aryl- or N-(1,2,4-triazol-yl)-phthalimides (4a-4i) have been synthesized starting from phthalic anhydride (1) and an appropriate amine (2a-2i). All compounds presented hypolipidemic activity, but compound 4d proved to be the most active and reduced plasma cholesterol and triglyceride levels in Swiss white mice significantly.
Synthesis and antibacterial activities of some 1,2,4-triazole derivatives
Ikizler, Aykut A.,Johansson,Bekircan,Celik
, p. 283 - 288 (2007/10/03)
Reactrions of 3-amino-1,2,4-triazole with some dicarboxylic acid anhydrides and diketones were studied. The structural assignments of the compounds obtained from the reactions are based on elemental analyses and spectral data. The compounds were screened for their in vitro antibacterial activities.
