59208-48-9 Usage
Uses
Used in Pharmaceutical Industry:
2-(5-methyl-1H-pyrazol-3-yl)-1H-isoindole-1,3(2H)-dione is used as a therapeutic agent for the treatment of gout and hyperuricemia. It is prescribed to patients who are unable to tolerate or do not respond well to other gout medications, providing an alternative treatment option. The primary application reason is its ability to inhibit the production of uric acid, thus preventing the formation of urate crystals that cause gout symptoms.
Used in Gout Management:
Febuxostat is used as a gout management medication to reduce the levels of uric acid in the body, which can help alleviate the pain and discomfort associated with gout attacks. Its application in this context is due to its effectiveness in preventing the formation of urate crystals that trigger gout flare-ups.
Used in Hyperuricemia Treatment:
In the treatment of hyperuricemia, 2-(5-methyl-1H-pyrazol-3-yl)-1H-isoindole-1,3(2H)-dione is used to lower uric acid levels, which can be a contributing factor to the development of gout and other health complications. Its application in this area is based on its ability to regulate uric acid production, thereby reducing the risk of uric acid-related health issues.
Check Digit Verification of cas no
The CAS Registry Mumber 59208-48-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,2,0 and 8 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 59208-48:
(7*5)+(6*9)+(5*2)+(4*0)+(3*8)+(2*4)+(1*8)=139
139 % 10 = 9
So 59208-48-9 is a valid CAS Registry Number.
59208-48-9Relevant academic research and scientific papers
(PYRAZOL-3-YL)-1,3,4-THIADIAZOL-2-AMINE AND (PYRAZOL-3-YL)-1,3,4-THIAZOL-2-AMINE COMPOUNDS
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Page/Page column 21-22, (2012/04/23)
A compound of Formula (I) wherein: either X is N and Y is CR5 or X is C and Y is S; Z is selected from N and CH; R1 is selected from H and Me; R2 is selected from H, OH, OMe and Me; each R3 is independently selected from C1-3alkyl, F, Cl, Br, CF3 and NH2; R4 is selected from Me, CF3, NO2 and CHF2; R5 is selected from H, Me and CHF2; R6 is selected from H and Me; and p is 0-3, compositions containing them, their use in therapy, for example in the treatment of tuberculosis, and methods for the preparation of such compounds, are provided.
PYRAZOLE DERIVATIVES AND USE THEREOF AS INHIBITORS OF STEAROYL-COA DESATURASE
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Page/Page column 15, (2009/03/07)
The present invention relates to compounds of formula (I) and salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds of formula (I) for inhibiting stearoyl-CoA desaturase (SCD) activity.
SUBSTITUTE 1, 6-NAPHTHYRIDINES FOR USE AS SCD INHIBITORS
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Page/Page column 33, (2009/06/27)
The present invention relates to substituted tetrahydronaphthyridine (THN) compounds of the formula (I) and salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds for inhibiting SCD activity.
