59210-42-3

Upstream product

• 109-01-3 1-methyl-piperazine 
• 59210-67-2 4-chloro-3-dimethylsulfamoylbenzonitrile 
• 59210-41-2 5-cyano-2-(4-methyl-piperazin-1-yl)-benzenesulfonamide 

Relevant academic research and scientific papers

Basically substituted 3-sulfamoylbenzoic acid derivatives and process for their preparation

Antihypertensively-active 3-sulfamoyl-4-piperazinyl-benzoic acids, optionally substituted in the 2-position by halogen or alkyl, and the esters, amides, and nitriles of these acids are disclosed, as is a method for making these compounds by the reaction of the corresponding 4-halogeno- or 4-alkyl-(or 4-aryl-) sulfonyloxy-benzoic acids (or their esters etc.) with piperazines.