59216-86-3Relevant academic research and scientific papers
Oxidative trifluoromethylation of unactivated olefins: An efficient and practical synthesis of α-trifluoromethyl-substituted ketones
Deb, Arghya,Manna, Srimanta,Modak, Atanu,Patra, Tuhin,Maity, Soham,Maiti, Debabrata
, p. 9747 - 9750 (2013/09/23)
An economical approach to α-CF3-substituted ketones, which are important intermediates in synthetic and medicinal chemistry, employs olefins and the readily available Langlois reagent (CF3SO 2Na). The reaction is operationally simple, proceeds at room temperature, and exhibits an excellent tolerance toward a wide variety of functional groups. Copyright
