59219-71-5Relevant academic research and scientific papers
Pd-Catalyzed Dehydrogenative Oxidation of Alcohols to Functionalized Molecules
Mori, Takamichi,Ishii, Chihiro,Kimura, Masanari
supporting information, p. 1709 - 1717 (2019/09/04)
A dehydrogenative oxidation reaction of primary alcohols to aldehydes catalyzed by a simple Pd/Xantphos catalytic system was developed under an argon or nitrogen atmosphere without oxidizing agents or hydrogen acceptors. The reaction product could be easily changed: under aerobic conditions, esters were obtained in aprotic solvents, whereas the corresponding carboxylic acids were produced in aqueous media. These oxidizing processes were applicable to the efficient synthesis of useful nitrogen-containing heterocyclic compounds such as indole, quinazoline, and benzimidazole via intramolecular versions of this reaction from amino alcohols.
Nickel-catalyzed Tishchenko reaction via hetero-nickelacycles by oxidative cyclization of aldehydes with nickel(0) complex
Ogoshi, Sensuke,Hoshimoto, Yoichi,Ohashi, Masato
supporting information; experimental part, p. 3354 - 3356 (2010/07/14)
A Ni(0)-catalyzed Tishchenko reaction which can be applied to a variety of aliphatic aldehydes (1°, 2°, 3°) and aromatic aldehydes was developed. The reaction might proceed via a hetero-nickelacycle intermediate.
Esterification of aldehydes and alcohols with pyridinium hydrobromide perbromide in water
Sayama, Shinsei,Onami, Tetsuo
, p. 2739 - 2745 (2007/10/03)
The direct esterification of aldehydes and alcohols was carried out with pyridinium hydrobromide perbromide in water at room temperature. A variety of aldehydes were converted to respective ester derivatives with alcohols such as methanol, 1,2-ethanediol, 1,3-propanediol. Further, a variety of aliphatic alcohols were also converted to the corresponding Tishchenko-like dimeric esters in good yields under the same reaction conditions.
