59222-96-7

Usage

InChI:InChI=1/C9H12O3S/c1-3-12-13(10,11)9-7-5-4-6-8(9)2/h4-7H,3H2,1-2H3

Upstream product

• 64-17-5 ethanol 
• 133-59-5 Toluene-2-sulfonyl chloride 
• 515-46-8 Ethyl benzenesulfonate 
• 74-88-4 methyl iodide 

Downstream Products

• 129303-65-7 ethyl 2-(2-hydroxy-2,2-diphenylethyl)benzenesulphonate 
• 129303-69-1 ethyl 2-(phenylsulphonylmethyl)benzenesulphonate 
• 129303-68-0 ethyl 2-(N-phenylcarbamoylmethyl)benzenesulphonate 
• 129303-64-6 ethyl 2-(2-hydroxy-2-phenylethyl)benzenesulphonate 
• 129303-66-8 ethyl 2-(ethoxycarbonylmethyl)benzenesulphonate 
• 129303-62-4 ethyl 2-(2-hydroxybutyl)benzenesulphonate 
• 129303-63-5 ethyl 2-(2-hydroxy-2-methylpropyl)benzenesulphonate 
• 129303-67-9 ethyl 2-(carboxymethyl)benzenesulphonate 

Relevant academic research and scientific papers

TRICYCLIC STEROID HORMONE NUCLEAR RECEPTOR MODULATORS

The present invention relates to methods of treating pathological disorders susceptible to steroid hormone nuclear receptor modulation comprising administering to a patient in need thereof an effective amount of a compound of the formula (I): or a pharmaceutically acceptable salt thereof. In addition, the present invention provides novel pharmaceutical compounds of Formula (I), including the pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions which comprise as an active ingredient a compound of Formula (I).

Sulphur-based Directed Benzylic Metallations: Lithiations of Alkylarenesulphonates

Benzylic anions (6) are obtained by regio-specific lithiations of ethyl 2-methylbenzenesulphonates.Evidence for the presence of the ethyl 2-lithiomethylbenzenesulphonates was obtained by efficient quenching studies with a range of electrophiles.Lithiations of the 2,4-dimethyl compound (9) gave the 2-lithiomethyl anion only, indicative of a predominant co-ordination mechanism in the lithiations.