59239-11-1Relevant academic research and scientific papers
Regiospecific Synthesis of Isoxazoles by the Reaction of α-Bromoenones with Hydroxylamine
Kashima, Choji,Shirai, Shun-ichi,Yoshiwara, Nobutoshi,Omote, Yoshimori
, p. 826 - 827 (1980)
In the reaction of α-bromoenones with hydroxylamine, the synthesis of isomeric isoxazoles could be controlled regiospecifically by changing the base.
Regioselective synthesis and side-chain metallation and elaboration of 3-aryl-5-alkylisoxazoles
Di Nunno, Leonardo,Scilimati, Antonio,Vitale, Paola
, p. 2659 - 2665 (2007/10/03)
A number of 3-aryl-5-alkylisoxazoles have been synthesized in high yields by reacting arylnitrile oxides with free enolate ions regioselectively obtained by metallation of various alkyl methyl ketones with LDA in THF at -78°C followed by dehydration. Inve
