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5924-05-0

1-Benzyl-3-(6-methyl-1,3-benzothiazol-2-yl)thiourea is a chemical compound with the molecular formula C16H16N2S2. It is a derivative of thiourea, featuring a benzyl group attached to the nitrogen atom at position 1 and a 6-methyl-1,3-benzothiazol-2-yl group at position 3. 1-benzyl-3-(6-methyl-1,3-benzothiazol-2-yl)thiourea is known for its potential applications in various fields, such as pharmaceuticals and materials science, due to its unique structure and properties. It is characterized by its ability to form coordination complexes with metal ions, which can be useful in the development of new drugs or as analytical reagents. The compound's synthesis typically involves the reaction of appropriate precursors, such as benzylamine and 6-methyl-1,3-benzothiazol-2-yl isothiocyanate, under controlled conditions. Its chemical properties, such as solubility and stability, can be influenced by the presence of the benzyl and benzothiazol moieties, making it a subject of interest for further research and development.

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  • 5924-05-0 Structure

  • Basic information

    1. Product Name: 1-benzyl-3-(6-methyl-1,3-benzothiazol-2-yl)thiourea
    2. Synonyms: 1-benzyl-3-(6-methyl-1,3-benzothiazol-2-yl)thiourea
    3. CAS NO:5924-05-0
    4. Molecular Formula:
    5. Molecular Weight: 313.447
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 5924-05-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-benzyl-3-(6-methyl-1,3-benzothiazol-2-yl)thiourea(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-benzyl-3-(6-methyl-1,3-benzothiazol-2-yl)thiourea(5924-05-0)
    11. EPA Substance Registry System: 1-benzyl-3-(6-methyl-1,3-benzothiazol-2-yl)thiourea(5924-05-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 5924-05-0(Hazardous Substances Data)

5924-05-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5924-05-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,2 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5924-05:
(6*5)+(5*9)+(4*2)+(3*4)+(2*0)+(1*5)=100
100 % 10 = 0
So 5924-05-0 is a valid CAS Registry Number.

5924-05-0Relevant articles and documents

Synthesis, characterization and biological evaluation of benzothiazoles and tetrahydrobenzothiazoles bearing urea or thiourea moieties as vasorelaxants and inhibitors of the insulin releasing process

Harrouche, Kamel,Renard, Jean-Francois,Bouider, Nafila,De Tullio, Pascal,Goffin, Eric,Lebrun, Philippe,Faury, Gilles,Pirotte, Bernard,Khelili, Smail

, p. 352 - 360 (2016)

A series of 1,3-benzothiazoles (series I) and 4,5,6,7-tetrahydro-1,3-benzothiazoles (series II) bearing an urea or a thiourea moiety at the 2-position were synthesized and tested as myorelaxants and inhibitors of insulin secretion. Several compounds (i.e. 13u and 13v) from series I showed a marked myorelaxant activity. Benzothiazoles bearing a strong electron withdrawing group (NO2, CN) at the 6-position and an alkyl group linked to the urea or the thiourea function at the 2-position were found to be the most potent compounds. The weak vasorelaxant activity of series II compounds evidenced the necessity of the presence of a complete aromatic heterocyclic system. The myorelaxant activity of some active compounds was reduced when measured on aorta rings precontracted by 80 mM KCl or by 30 mM KCl in the presence of 10 μM glibenclamide, suggesting the involvement of KATP channels in the vasorelaxant effect. Some compounds of series I tested on rat pancreatic islets provoked a marked inhibition of insulin secretion, among which 13a exhibited a clear tissue selectivity for pancreatic β-cells.

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