592516-98-8

Basic information

• Product Name: 1,4,8,11-Tetraazacyclotetradecane-5,7,12-trione, 1,1'-[1,4-phenylenebis(methylene)]bis-
• CAS NO: 592516-98-8
• Molecular Formula: C28H42N8O6
• Molecular Weight: 586.691
• Mol File: 592516-98-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,4,8,11-Tetraazacyclotetradecane-5,7,12-trione, 1,1'-[1,4-phenylenebis(methylene)]bis-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4,8,11-Tetraazacyclotetradecane-5,7,12-trione, 1,1'-[1,4-phenylenebis(methylene)]bis-(592516-98-8)
• EPA Substance Registry System: 1,4,8,11-Tetraazacyclotetradecane-5,7,12-trione, 1,1'-[1,4-phenylenebis(methylene)]bis-(592516-98-8)

Safety Data

• Hazardous Substances Data: 592516-98-8(Hazardous Substances Data)

Upstream product

• 623-24-5 1,4-bis(bromomethyl)benzene 
• 85828-27-9 1,4,8,11-tetraazacyclotetradecane-5,7,12-trione 
• 592516-95-5 N-(2-aminoethyl)-3-[(2-aminoethyl)amino]propionamide 

Downstream Products

• 110078-46-1 1-[4-(1,4,8,11-tetraazacyclotetradecan-1-ylmethyl)benzyl]-1,4,8,11-tetraazacyclotetradecane 

Relevant articles and documents

Direct synthesis of 1,1′-[1,4-phenylenebis(methylene)]-bis-1,4,8,11- tetraazacyclotetradecane octahydrochloride (AMD 3100) without the use of protecting groups

A four-step synthesis of the title compound starting from methyl acrylate, ethylenediamine, and dimethyl malonate is reported. The synthesis can be run on a multigram scale and is operationally simple. The use of protecting groups is avoided by utilizing