592533-35-2Relevant academic research and scientific papers
Synthesis and biological evaluation of new UDP-GalNAc analogues for the study of polypeptide-α-GalNAc-transferases
Busca, Patricia,Piller, Veronique,Piller, Friedrich,Martin, Olivier R.
, p. 1853 - 1856 (2007/10/03)
A series of three O-methylated UDP-GalNAc analogues have been synthesised using a divergent strategy from a 3,6-di-O-pivaloyl GlcNAc derivative. The biological activity of these probes toward polypeptide-α-GalNAc-transferase T1 has been investigated. This study shows that this glycosyltransferase exhibits a very high substrate specificity.
