592534-83-3Relevant articles and documents
Synthesis and biological activities of prenylated tyrosine derivatives, the metabolites of Pithomyces ellis
Venkateswarlu, Somepalli,Panchagnula, Gopala K.,Subbaraju, Gottumukkala V.
, p. 1063 - 1066 (2007/10/03)
2-[4-(2E)-3-Methylbut-2-enyloxy)phenyl]ethan-1-ol 3 and 3-[4-(2E)-3-methylbut-2-enyloxy) phenyl]-2-(acetylamino)propanoic acid 8 have been synthesized from 4-hydroxyphenylacetic acid 1, L-tyrosine 4, respectively, with an overall yield of 55% and 37%. The spectral data of synthetic 3 and 8 are in good agreement with those of natural 3 and 8, respectively. These synthetic 3 and 8 show significant brine shrimp lethality, but weak antioxidant and antibacterial activities.