Welcome to LookChem.com Sign In|Join Free

CAS

  • or

592542-51-3

Post Buying Request

592542-51-3 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

592542-51-3 Usage

General Description

4-Methoxy-3-nitrobenzylsulfonylacetic acid is a chemical compound with the molecular formula C11H11NO7S. It is a derivative of 4-methoxybenzylsulfonylacetic acid, with a nitro group substituent at the 3-position of the benzene ring. 4-Methoxy-3-nitrobenzylsulfonylacetic acid has been studied for its potential pharmacological and biological activities, including its use as a reagent in organic synthesis and as a potential antihypertensive agent. Its chemical structure and properties make it a promising candidate for further research and development in medicinal and pharmaceutical applications.

Check Digit Verification of cas no

The CAS Registry Mumber 592542-51-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,9,2,5,4 and 2 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 592542-51:
(8*5)+(7*9)+(6*2)+(5*5)+(4*4)+(3*2)+(2*5)+(1*1)=173
173 % 10 = 3
So 592542-51-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H11NO7S/c1-18-9-3-2-7(4-8(9)11(14)15)5-19(16,17)6-10(12)13/h2-4H,5-6H2,1H3,(H,12,13)

592542-51-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-((4-Methoxy-3-nitrobenzyl)sulfonyl)acetic acid

1.2 Other means of identification

Product number -
Other names 2-[(4-methoxy-3-nitrophenyl)methylsulfonyl]acetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:592542-51-3 SDS

592542-51-3Relevant articles and documents

Platinum-Based Modification of Styrylbenzylsulfones as Multifunctional Antitumor Agents: Targeting the RAS/RAF Pathway, Enhancing Antitumor Activity, and Overcoming Multidrug Resistance

Liu, Zhikun,Wang, Meng,Wang, Hengshan,Fang, Lei,Gou, Shaohua

, p. 186 - 204 (2020/01/22)

Inhibiting/disturbing the RAS/RAF pathway may benefit the treatment of cancer and overcome the resistance. Utilizing such a pathway as the target, nine styrylbenzylsulfone derivatives generated from the platinum-based modification of the side chain of Rig

Design, synthesis and evaluation of 3-substituted coumarin derivatives as anti-inflammatory agents

Liu, Shuchen,Peng, Tao,Sun, Yunbo,Wang, Gang,Wang, Lin,Wang, Tao,Wen, Xiaoxue,Zhang, Shouguo

, p. 443 - 446 (2020/09/09)

Coumarin moiety has garnered momentous attention especially in the design of compounds with significant biological activities. In this work, a series of 3-substituted coumarin derivatives 6a-6l were synthesized and fully characterized. Most of the compoun

Discovery of a clinical stage multi-kinase inhibitor sodium (E)-2-{2-methoxy-5-[(2′,4′,6′-trimethoxystyrylsulfonyl)methyl] phenylamino}acetate (ON 01910.Na): Synthesis, structure-activity relationship, and biological activity

Reddy, M. V. Ramana,Venkatapuram, Padmavathi,Mallireddigari, Muralidhar R.,Pallela, Venkat R.,Cosenza, Stephen C.,Robell, Kimberly A.,Akula, Balaiah,Hoffman, Benjamin S.,Reddy, E. Premkumar

, p. 6254 - 6276 (2011/11/01)

Cyclin D proteins are elevated in many cancer cells, and targeted deletion of cyclin D1 gene in the mammary tissues protects mice from breast cancer. Accordingly, there is an increasing awareness of this novel nonenzymatic target for cancer therapeutics. We have developed novel, nonalkylating styrylbenzylsulfones that induce cell death in wide variety of cancer cells without affecting the proliferation and survival of normal cells. The development of derivatized styrylbenzylsulfones followed logically from a tumor cell cytotoxicity screen performed in our laboratory that did not have an a priori target profile. Modifications of some of the precursor molecules led to lead optimization with regard to tumor cell cytotoxicity. In this report we describe the synthesis and structure-activity relationships of novel, nonalkylating (E)-styrylbenzylsulfones and the development of the novel anticancer agent sodium (E)-2-{2-methoxy-5-[(2′,4′,6′- trimethoxystyrylsulfonyl)methyl]phenylamino}acetate (ON 01910.Na), which is in phase III trials for myelodysplastic syndromes (MDS) associated with aberrant expression of cyclin D proteins.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 592542-51-3