59275-39-7Relevant academic research and scientific papers
Surface effects in the esterification of 9-pyrenebutyric acid within a glass micro reactor
Brivio, Monica,Oosterbroek, R. Edwin,Verboom, Willem,Goedbloed, Martijn H.,Van Den Berg, Albert,Reinhoudt, David N.
, p. 1924 - 1925 (2003)
Surface phenomena are an important contribution to the chip effect , leading to higher yields and shorter reaction times, as demonstrated for the acid-catalysed esterification of 9-pyrenebutyric acid within a glass fabricated micro reactor.
Photoinduced electron transfer between non-native donor-acceptor moieties incorporated in synthetic polypeptide aggregates.
Jones 2nd., Guilford,Vullev, Valentine I
, p. 4001 - 4004 (2002)
A series of analogous photoactive polypeptides that form helical homo and hetero aggregates in aqueous media were prepared. A pyrenyl ketone (the principal chromophore and an electron acceptor) was attached to the N-termini. An electron donor, amidoethylcarbazole, was introduced as a side chain of a non-native amino acid, NCb, 14 residues away. Photoinduced electron-transfer rate constants of the order of 10(8) s(-1) between remote pyrene and carbazole were measured. [structure: see text]
Bio-orthogonal phosphatidylserine conjugates for delivery and imaging applications
Lampkins, Andrew J.,O'Neil, Edward J.,Smith, Bradley D.
, p. 6053 - 6058 (2008/12/22)
(Chemical Equation Presented) The syntheses of phosphatidylserine (PS) conjugates are described, including fluorescent derivatives for potential cellular delivery and bioimaging applications. Installation of terminal functional groups (amine, thiol, or alkyne) onto the sn-2 chain provides reactive sites for bio-orthogonal conjugation of cargo with suitably protected PS derivatives. An amine-containing PS forms amide bonds with peptidic cargo, a thiol derivative is designed for conjugation to cargo that contain α-halo carbonyls or Michael acceptors, and the terminal alkyne PS analogue permits "click" conjugation with any azide-tagged molecule. This latter conjugation method is quite versatile as it can be performed without PS headgroup protection, in aqueous media, and with acid-labile cargo.
