59297-29-9

Usage

Uses

Used in Organic Synthesis:
1-Bromo-3-(bromomethyl)-5-methoxybenzene is used as a key intermediate in organic synthesis for the production of various organic compounds. Its unique structure with bromine and methoxy groups allows for further chemical reactions and modifications, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
In pharmaceutical research, 1-Bromo-3-(bromomethyl)-5-methoxybenzene is utilized as a building block for the development of biologically active molecules. Its presence in the molecular structure can contribute to the pharmacological properties of the final drug, potentially leading to the discovery of new therapeutic agents.
Used in the Synthesis of Pharmaceuticals:
1-Bromo-3-(bromomethyl)-5-methoxybenzene is employed as a reagent in the synthesis of pharmaceuticals. Its bromine and methoxy groups provide opportunities for chemical reactions that can lead to the formation of pharmaceutically relevant compounds, contributing to the development of new drugs.
Used in the Production of Agrochemicals:
1-BroMo-3-(broMoMethyl)-5-Methoxybenzene is also used as a starting material in the production of agrochemicals. Its chemical properties and reactivity make it suitable for the synthesis of various agrochemicals, which can be used in agriculture for pest control and crop protection.

Upstream product

• 262450-64-6 (3-bromo-5-methoxyphenyl)methanol 
• 74204-00-5 3-bromo-5-methylphenol 
• 157893-14-6 3-bromo-5-methoxybenzoic acid 
• 29578-83-4 3-bromo-5-methoxytoluene 

Downstream Products

• 762292-58-0 C₁₇H₁₆BrNO₂ 
• 729614-63-5 methyl 5-(3-bromo-5-methoxybenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylate 
• 1176327-09-5 diethyl 3-bromo-5-methoxybenzylphosphonate 
• 123018-27-9 2-(3-bromo-5-methoxyphenyl)acetonitrile 
• 262450-67-9 2-(3-bromo-5-methoxyphenyl)ethylamine 
• 1220694-87-0 8-bromo-6-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 1177558-46-1 (3-bromo-5-methoxyphenyl)methanamine 

Relevant academic research and scientific papers

Pyrrolopyrazole derivative, preparation method and medical application thereof

The invention relates to pyrrolopyrazole derivative, a preparation method and application thereof in medicines. Specifically, the invention relates to a new pyrrolopyrazole derivative as shown in a general formula (I), a preparation method and application of the pyrrolopyrazole derivative or a pharmaceutical composition containing the pyrrolopyrazole derivative as a therapeutic agent, particularlyas a gastric acid secretion inhibitor and potassium-competitive acid blockers (P-CABs) in biological medicines. Specifically, the substituents (R1, R2, R3 and R4) in the general formula (I) are the same as the definitions in the specification.

Pyrrolopyrazole derivatives and preparation method thereof, and application of pyrrolopyrazole derivatives in medicines

The invention relates to pyrrolopyrazole derivatives and a preparation method thereof, and application of the pyrrolopyrazole derivatives in medicines. Specifically, the invention relates to novel pyrrolopyrazole derivatives as shown in a general formula (I) in the specification, the preparation method of the pyrrolopyrazole derivatives and application of the pyrrolopyrazole derivatives or pharmaceutical compositions containing the pyrrolopyrazole derivatives as therapeutic agents, particularly as gastric acid secretion inhibitors and potassium ion competitive acid blockers (P-CABs) in biological medicines. All the substituents (R1, R2, R3 and R4) in the general formula (I) are as defined in the specification.

SMALL MOLECULE AUTOPHAGY INDUCERS FOR THE TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES

Disclosed herein are compounds and methods for treating cancer and neurodegenerative diseases. In some examples, the compounds increase autophagy.

TYK2 INHIBITORS AND USES THEREOF

Described herein are compounds that are useful in treating a TYK2-mediated disorder. In some embodiments, the TYK2-mediated disorder is an autoimmune disorder, an inflammatory disorder, a proliferative disorder, an endocrine disorder, a neurological disorder, or a disorder associated with transplantation.

Pyrrolopyrazole derivative and preparation method thereof, and applications of pyrrolopyrazole derivative in medicine

The present invention relates to a pyrrolopyrazole derivative and a preparation method thereof, and applications of the pyrrolopyrazole derivative in medicine, particularly to a class of new pyrrolopyrazole derivatives represented by a general formula (I), and a preparation method thereof, and uses of the pyrrolopyrazole derivatives or pharmaceutical compositions containing the pyrrolopyrazole derivatives as treating agents, particularly as gastric acid secretion inhibitors and potassium ion competitive acid blockers (P-CABs) in biomedicine, wherein various substituents (R, R and R) and the groups (X, Y and Z) in the formula (I) are defined in the specification.

HETEROCYCLIC CARBOXYLIC ACIDS AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE

The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R5, R6, R7, R8, R9, B, V, W, X, Y, Z and m are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

SUBSTITUTED HETEROCYCLIC SULFONAMIDE COMPOUNDS USEFUL AS TRPA1 MODULATORS

The invention is concerned with the compounds of formula I or II: and salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I or II as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

ALKOXY PYRAZOLES AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS

The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6 and R7 are as defined herein. The inventi

8-Substituted isoquinoline derivative and the use thereof

The present invention relates to a compound represented by the following formula (1): wherein D1, A1, D2, R1, D3, and R2 each have the same meaning as defined in the present specification or a salt thereof. The compound represented by the formula (1) or a salt thereof has an IKKβ inhibiting activity and the like and is useful for the prevention and/or treatment of IKKβ-associated diseases or symptoms and the like.

BENZYLPIPERIZINE COMPOUND

Disclosed is a benzylpiperizine compound represented by formula (1) or a pharmaceutically acceptable salt thereof, which is useful as a medicinal agent such as an antidepressant agent. (In the formula (1), R1 represents a hydrogen atom or a met