59321-60-7Relevant academic research and scientific papers
A mild and efficient method for the stereoselective formation of C-O bonds: Palladium-catalyzed allylic etherification using zinc(II) alkoxides
Kim, Hahn,Lee, Chulbom
, p. 4369 - 4371 (2002)
(equation presented) A highly chemo-and stereoselective palladium-catalyzed allylic etherification reaction is described. The use of zinc(II) alkoxides proved effective in promoting the addition of the oxygen nucleophile derived from aliphatic alcohols to η3-allylpalladium complexes. Using diethylzinc (0.5 equiv), 5 mol % of Pd(OAc)2, and 7.5 mol % of 2-di(tert-butyl)phosphinobiphenyl in THF, the cross-coupling reaction between various aliphatic alcohols and allylic acetates proceeded at ambient temperature to furnish allylic ethers with high stereoselectivity.
Umpolung of the reactivity of allylsilanes. Palladium(II) catalyzed cyclization of allylsilyl alcohols: A new route to substituted 2- vinyltetrahydrofurans
MacSári, István,Szabó, Kálmán J.
, p. 1119 - 1122 (2007/10/03)
Functionalized allylsilanes 1-4 undergo palladium(II) catalyzed ring closure to afford 4- and/or 5-substituted 2-vinyltetrahydrofurans (5-8) under mild conditions. The catalytic reactions proceed through (η3- allyl)palladium intermediates forme
