59325-98-3Relevant articles and documents
Glycosidic cleavage from anaerobic saponification of the heptaacetate of daunomycin hydroquinone
Schweitzer,Koch
, p. 5446 - 5452 (2007/10/02)
-
Reaction of the quinone methide from reductive glycosidic cleavage of daunomycin with molecular oxygen. Evidence for semiquinone methide formation
Gaudiano, Giorgio,Koch, Tad H.
, p. 9423 - 9425 (2007/10/02)
-
AN EFFICIENT, REGIOSPECIFIC SYNTHESIS OF (+/-)-DAUNOMYCINONE
Kelly, T. Ross,Ananthasubramanian, L.,Borah, Kripinath,Gillard, John W.,Goerner, Richard N.,et al.
, p. 4569 - 4578 (2007/10/02)
The development of a general strategy for the control of regiochemistry in the Diels-Alder reactions of substituted naphthazarins is described.Application of this strategy to the synthesis of (+/-)-daunomycinone (2) employs two successive regiochemically controlled Diels-Alder reactions and leads to a ten-step, regiospecific synthesis of (+/-)-2 in 36percent overall yield (Scheme 4).